Hallak H - Search Results

1

Matrix metalloproteinase inhibition during the development of congestive heart failure : effects on left ventricular dimensions and function.

Spinale FG, Coker ML, Krombach SR, Mukherjee R, Hallak H, Houck WV, Clair MJ, Kribbs SB, Johnson LL, Peterson JT, Zile MR. Spinale FG, et al. Among authors: hallak h. Circ Res. 1999 Aug 20;85(4):364-76. doi: 10.1161/01.res.85.4.364. Circ Res. 1999. PMID: 10455065

2

Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure.

Peterson JT, Hallak H, Johnson L, Li H, O'Brien PM, Sliskovic DR, Bocan TM, Coker ML, Etoh T, Spinale FG. Peterson JT, et al. Among authors: hallak h. Circulation. 2001 May 8;103(18):2303-9. doi: 10.1161/01.cir.103.18.2303. Circulation. 2001. PMID: 11342481

3

Angiotensin-converting enzyme and matrix metalloproteinase inhibition with developing heart failure: comparative effects on left ventricular function and geometry.

McElmurray JH 3rd, Mukherjee R, New RB, Sampson AC, King MK, Hendrick JW, Goldberg A, Peterson TJ, Hallak H, Zile MR, Spinale FG. McElmurray JH 3rd, et al. Among authors: hallak h. J Pharmacol Exp Ther. 1999 Nov;291(2):799-811. J Pharmacol Exp Ther. 1999. PMID: 10525103

4

Structure-activity relationships and pharmacokinetic analysis for a series of potent, systemically available biphenylsulfonamide matrix metalloproteinase inhibitors.

O'Brien PM, Ortwine DF, Pavlovsky AG, Picard JA, Sliskovic DR, Roth BD, Dyer RD, Johnson LL, Man CF, Hallak H. O'Brien PM, et al. Among authors: hallak h. J Med Chem. 2000 Jan 27;43(2):156-66. doi: 10.1021/jm9903141. J Med Chem. 2000. PMID: 10649971

5

Molecular sieving and mass spectroscopy reveal enhanced collagen degradation in rabbit atheroma.

Chen J, Kindt E, Hallak H, Peterson JT, Rosebury WS, Hubbel AM, Bocan TM, Rekhter MD. Chen J, et al. Among authors: hallak h. Atherosclerosis. 2001 Dec;159(2):289-95. doi: 10.1016/s0021-9150(01)00509-3. Atherosclerosis. 2001. PMID: 11730808

6

Hypercholesterolemia causes mechanical weakening of rabbit atheroma : local collagen loss as a prerequisite of plaque rupture.

Rekhter MD, Hicks GW, Brammer DW, Hallak H, Kindt E, Chen J, Rosebury WS, Anderson MK, Kuipers PJ, Ryan MJ. Rekhter MD, et al. Among authors: hallak h. Circ Res. 2000 Jan 7-21;86(1):101-8. doi: 10.1161/01.res.86.1.101. Circ Res. 2000. PMID: 10625311

7

Structure-activity relationships in a series of orally active gamma-hydroxy butenolide endothelin antagonists.

Patt WC, Edmunds JJ, Repine JT, Berryman KA, Reisdorph BR, Lee C, Plummer MS, Shahripour A, Haleen SJ, Keiser JA, Flynn MA, Welch KM, Reynolds EE, Rubin R, Tobias B, Hallak H, Doherty AM. Patt WC, et al. Among authors: hallak h. J Med Chem. 1997 Mar 28;40(7):1063-74. doi: 10.1021/jm9606507. J Med Chem. 1997. PMID: 9089328

8

Structure-activity relationships for a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors.

Hamby JM, Connolly CJ, Schroeder MC, Winters RT, Showalter HD, Panek RL, Major TC, Olsewski B, Ryan MJ, Dahring T, Lu GH, Keiser J, Amar A, Shen C, Kraker AJ, Slintak V, Nelson JM, Fry DW, Bradford L, Hallak H, Doherty AM. Hamby JM, et al. Among authors: hallak h. J Med Chem. 1997 Jul 18;40(15):2296-303. doi: 10.1021/jm970367n. J Med Chem. 1997. PMID: 9240345

9

2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity.

Klutchko SR, Hamby JM, Boschelli DH, Wu Z, Kraker AJ, Amar AM, Hartl BG, Shen C, Klohs WD, Steinkampf RW, Driscoll DL, Nelson JM, Elliott WL, Roberts BJ, Stoner CL, Vincent PW, Dykes DJ, Panek RL, Lu GH, Major TC, Dahring TK, Hallak H, Bradford LA, Showalter HD, Doherty AM. Klutchko SR, et al. Among authors: hallak h. J Med Chem. 1998 Aug 13;41(17):3276-92. doi: 10.1021/jm9802259. J Med Chem. 1998. PMID: 9703473

10

Synthesis and tyrosine kinase inhibitory activity of a series of 2-amino-8H-pyrido[2,3-d]pyrimidines: identification of potent, selective platelet-derived growth factor receptor tyrosine kinase inhibitors.

Boschelli DH, Wu Z, Klutchko SR, Showalter HD, Hamby JM, Lu GH, Major TC, Dahring TK, Batley B, Panek RL, Keiser J, Hartl BG, Kraker AJ, Klohs WD, Roberts BJ, Patmore S, Elliott WL, Steinkampf R, Bradford LA, Hallak H, Doherty AM. Boschelli DH, et al. Among authors: hallak h. J Med Chem. 1998 Oct 22;41(22):4365-77. doi: 10.1021/jm980398y. J Med Chem. 1998. PMID: 9784112

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