Lima WF - Search Results

1

Highly efficient endonucleolytic cleavage of RNA by a Cys(2)His(2) zinc-finger peptide.

Lima WF, Crooke ST. Lima WF, et al. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10010-5. doi: 10.1073/pnas.96.18.10010. Proc Natl Acad Sci U S A. 1999. PMID: 10468553 Free PMC article.

2

Binding affinity and specificity of Escherichia coli RNase H1: impact on the kinetics of catalysis of antisense oligonucleotide-RNA hybrids.

Lima WF, Crooke ST. Lima WF, et al. Biochemistry. 1997 Jan 14;36(2):390-8. doi: 10.1021/bi962230p. Biochemistry. 1997. PMID: 9003192

3

The influence of antisense oligonucleotide-induced RNA structure on Escherichia coli RNase H1 activity.

Lima WF, Mohan V, Crooke ST. Lima WF, et al. J Biol Chem. 1997 Jul 18;272(29):18191-9. doi: 10.1074/jbc.272.29.18191. J Biol Chem. 1997. PMID: 9218455 Free article.

4

Cleavage of single strand RNA adjacent to RNA-DNA duplex regions by Escherichia coli RNase H1.

Lima WF, Crooke ST. Lima WF, et al. J Biol Chem. 1997 Oct 31;272(44):27513-6. doi: 10.1074/jbc.272.44.27513. J Biol Chem. 1997. PMID: 9346880 Free article.

5

Properties of cloned and expressed human RNase H1.

Wu H, Lima WF, Crooke ST. Wu H, et al. Among authors: lima wf. J Biol Chem. 1999 Oct 1;274(40):28270-8. doi: 10.1074/jbc.274.40.28270. J Biol Chem. 1999. PMID: 10497183 Free article.

6

Investigating the structure of human RNase H1 by site-directed mutagenesis.

Wu H, Lima WF, Crooke ST. Wu H, et al. Among authors: lima wf. J Biol Chem. 2001 Jun 29;276(26):23547-53. doi: 10.1074/jbc.M009676200. Epub 2001 Apr 23. J Biol Chem. 2001. PMID: 11319219 Free article.

7

Preparation and use of ZFY-6 zinc finger ribonuclease.

Lima WF, Crooke ST. Lima WF, et al. Methods Enzymol. 2001;341:490-500. doi: 10.1016/s0076-6879(01)41172-4. Methods Enzymol. 2001. PMID: 11582800 No abstract available.

8

Human RNase H1 activity is regulated by a unique redox switch formed between adjacent cysteines.

Lima WF, Wu H, Nichols JG, Manalili SM, Drader JJ, Hofstadler SA, Crooke ST. Lima WF, et al. J Biol Chem. 2003 Apr 25;278(17):14906-12. doi: 10.1074/jbc.M211279200. Epub 2002 Dec 8. J Biol Chem. 2003. PMID: 12473655 Free article.

9

Human RNase H1 uses one tryptophan and two lysines to position the enzyme at the 3'-DNA/5'-RNA terminus of the heteroduplex substrate.

Lima WF, Wu H, Nichols JG, Prakash TP, Ravikumar V, Crooke ST. Lima WF, et al. J Biol Chem. 2003 Dec 12;278(50):49860-7. doi: 10.1074/jbc.M306543200. Epub 2003 Sep 23. J Biol Chem. 2003. PMID: 14506260 Free article.

10

Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs.

Wu H, Lima WF, Zhang H, Fan A, Sun H, Crooke ST. Wu H, et al. Among authors: lima wf. J Biol Chem. 2004 Apr 23;279(17):17181-9. doi: 10.1074/jbc.M311683200. Epub 2004 Feb 11. J Biol Chem. 2004. PMID: 14960586 Free article.

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