He JX - Search Results

1

The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: part 2.

Cody WL, Augelli-Szafran CE, Berryman KA, Cai C, Doherty AM, Edmunds JJ, He JX, Narasimhan LS, Penvose-Yi J, Plummer JS, Rapundalo ST, Rubin JR, Van Huis CA, Leblond L, Winocour PD, Siddiqui MA. Cody WL, et al. Among authors: he jx. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2503-8. doi: 10.1016/s0960-894x(99)00419-9. Bioorg Med Chem Lett. 1999. PMID: 10498197

2

Design of a functional hexapeptide antagonist of endothelin.

Cody WL, Doherty AM, He JX, DePue PL, Rapundalo ST, Hingorani GA, Major TC, Panek RL, Dudley DT, Haleen SJ, et al. Cody WL, et al. Among authors: he jx. J Med Chem. 1992 Aug 21;35(17):3301-3. doi: 10.1021/jm00095a029. J Med Chem. 1992. PMID: 1324321 No abstract available.

3

Structure-activity relationships of the potent combined endothelin-A/endothelin-B receptor antagonist Ac-DDip16-Leu-Asp-Ile-Ile-Trp21: development of endothelin-B receptor selective antagonists.

Cody WL, He JX, DePue PL, Waite LA, Leonard DM, Sefler AM, Kaltenbronn JS, Haleen SJ, Walker DM, Flynn MA, et al. Cody WL, et al. Among authors: he jx. J Med Chem. 1995 Jul 21;38(15):2809-19. doi: 10.1021/jm00015a003. J Med Chem. 1995. PMID: 7636842

4

Structure-activity relationships of C-terminal endothelin hexapeptide antagonists.

Doherty AM, Cody WL, DePue PL, He JX, Waite LA, Leonard DM, Leitz NL, Dudley DT, Rapundalo ST, Hingorani GP, et al. Doherty AM, et al. Among authors: he jx. J Med Chem. 1993 Sep 3;36(18):2585-94. doi: 10.1021/jm00070a001. J Med Chem. 1993. PMID: 8410970

5

Design of a potent combined pseudopeptide endothelin-A/endothelin-B receptor antagonist, Ac-DBhg16-Leu-Asp-Ile-[NMe]Ile-Trp21 (PD 156252): examination of its pharmacokinetic and spectral properties.

Cody WL, He JX, Reily MD, Haleen SJ, Walker DM, Reyner EL, Stewart BH, Doherty AM. Cody WL, et al. Among authors: he jx. J Med Chem. 1997 Jul 4;40(14):2228-40. doi: 10.1021/jm970161m. J Med Chem. 1997. PMID: 9216842

6

Potent and selective bicyclic lactam inhibitors of thrombin: Part 2: P1 modifications.

Plummer JS, Berryman KA, Cai C, Cody WL, DiMaio J, Doherty AM, Edmunds JJ, He JX, Holland DR, Levesque S, Kent DR, Narasimhan LS, Rubin JR, Rapundalo ST, Siddiqui MA, Susser AJ, St-Denis Y, Winocour PD. Plummer JS, et al. Among authors: he jx. Bioorg Med Chem Lett. 1998 Dec 1;8(23):3409-14. doi: 10.1016/s0960-894x(98)00613-1. Bioorg Med Chem Lett. 1998. PMID: 9873743

7

The design of potent and selective inhibitors of thrombin utilizing a piperazinedione template: part 1.

Cody WL, Cai C, Doherty AM, Edmunds JJ, He JX, Narasimhan LS, Plummer JS, Rapundalo ST, Rubin JR, Van Huis CA, St-Denis Y, Winocour PD, Siddiqui MA. Cody WL, et al. Among authors: he jx. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2497-502. doi: 10.1016/s0960-894x(99)00418-7. Bioorg Med Chem Lett. 1999. PMID: 10498196

8

In vitro and in vivo studies with a series of hexapeptide endothelin antagonists.

Doherty AM, Cody WL, He JX, DePue PL, Cheng XM, Welch KM, Flynn MA, Reynolds EE, LaDouceur DM, Davis LS, et al. Doherty AM, et al. Among authors: he jx. J Cardiovasc Pharmacol. 1993;22 Suppl 8:S98-102. doi: 10.1097/00005344-199322008-00027. J Cardiovasc Pharmacol. 1993. PMID: 7510009

9

Design and structure-activity relationships of C-terminal cyclic neurotensin fragment analogues.

Sefler AM, He JX, Sawyer TK, Holub KE, Omecinsky DO, Reily MD, Thanabal V, Akunne HC, Cody WL. Sefler AM, et al. Among authors: he jx. J Med Chem. 1995 Jan 20;38(2):249-57. doi: 10.1021/jm00002a006. J Med Chem. 1995. PMID: 7830267

10

Truncated analogues of endothelin and sarafotoxin are selective for the ETB receptor subtype.

Heyl DL, Cody WL, He JX, Flynn MA, Welch KM, Reynolds EE, Doherty AM. Heyl DL, et al. Among authors: he jx. Pept Res. 1993 Sep-Oct;6(5):238-41. Pept Res. 1993. PMID: 8257799

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