Spilman PR - Search Results

1

PrPc glycoform heterogeneity as a function of brain region: implications for selective targeting of neurons by prion strains.

DeArmond SJ, Qiu Y, Sànchez H, Spilman PR, Ninchak-Casey A, Alonso D, Daggett V. DeArmond SJ, et al. Among authors: spilman pr. J Neuropathol Exp Neurol. 1999 Sep;58(9):1000-9. doi: 10.1097/00005072-199909000-00010. J Neuropathol Exp Neurol. 1999. PMID: 10499442

2

The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system.

Bouzamondo-Bernstein E, Hopkins SD, Spilman P, Uyehara-Lock J, Deering C, Safar J, Prusiner SB, Ralston HJ 3rd, DeArmond SJ. Bouzamondo-Bernstein E, et al. J Neuropathol Exp Neurol. 2004 Aug;63(8):882-99. doi: 10.1093/jnen/63.8.882. J Neuropathol Exp Neurol. 2004. PMID: 15330342

3

A gamma-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains.

Spilman P, Lessard P, Sattavat M, Bush C, Tousseyn T, Huang EJ, Giles K, Golde T, Das P, Fauq A, Prusiner SB, Dearmond SJ. Spilman P, et al. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10595-600. doi: 10.1073/pnas.0803671105. Epub 2008 Jul 22. Proc Natl Acad Sci U S A. 2008. PMID: 18647832 Free PMC article.

4

Evaluation of an Allosteric BACE Inhibitor Peptide to Identify Mimetics that Can Interact with the Loop F Region of the Enzyme and Prevent APP Cleavage.

Campagna J, Vadivel K, Jagodzinska B, Jun M, Bilousova T, Spilman P, John V. Campagna J, et al. J Mol Biol. 2018 May 25;430(11):1566-1576. doi: 10.1016/j.jmb.2018.04.002. Epub 2018 Apr 10. J Mol Biol. 2018. PMID: 29649434

5

The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model.

Spilman P, Descamps O, Gorostiza O, Peters-Libeu C, Poksay KS, Matalis A, Campagna J, Patent A, Rao R, John V, Bredesen DE. Spilman P, et al. Brain Res. 2014 Mar 10;1551:25-44. doi: 10.1016/j.brainres.2013.12.029. Epub 2013 Dec 31. Brain Res. 2014. PMID: 24389031 Free PMC article.

6

Paradoxical effect of TrkA inhibition in Alzheimer's disease models.

Zhang Q, Descamps O, Hart MJ, Poksay KS, Spilman P, Kane DJ, Gorostiza O, John V, Bredesen DE. Zhang Q, et al. J Alzheimers Dis. 2014;40(3):605-617. doi: 10.3233/JAD-130017. J Alzheimers Dis. 2014. PMID: 24531152 Free PMC article.

7

sAβPPα is a Potent Endogenous Inhibitor of BACE1.

Peters-Libeu C, Campagna J, Mitsumori M, Poksay KS, Spilman P, Sabogal A, Bredesen DE, John V. Peters-Libeu C, et al. J Alzheimers Dis. 2015;47(3):545-55. doi: 10.3233/JAD-150282. J Alzheimers Dis. 2015. PMID: 26401691

8

Netrin-1 Interrupts Amyloid-β Amplification, Increases sAβPPα in vitro and in vivo, and Improves Cognition in a Mouse Model of Alzheimer's Disease.

Spilman PR, Corset V, Gorostiza O, Poksay KS, Galvan V, Zhang J, Rao R, Peters-Libeu C, Vincelette J, McGeehan A, Dvorak-Ewell M, Beyer J, Campagna J, Bankiewicz K, Mehlen P, John V, Bredesen DE. Spilman PR, et al. J Alzheimers Dis. 2016 Mar 8;52(1):223-42. doi: 10.3233/JAD-151046. J Alzheimers Dis. 2016. PMID: 27060954

9

Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.

Zhu C, Bilousova T, Focht S, Jun M, Elias CJ, Melnik M, Chandra S, Campagna J, Cohn W, Hatami A, Spilman P, Gylys KH, John V. Zhu C, et al. Mol Brain. 2021 Apr 19;14(1):70. doi: 10.1186/s13041-021-00776-9. Mol Brain. 2021. PMID: 33875010 Free PMC article.

10

A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.

Campagna J, Spilman P, Jagodzinska B, Bai D, Hatami A, Zhu C, Bilousova T, Jun M, Elias CJ, Pham J, Cole G, LaDu MJ, Jung ME, Bredesen DE, John V. Campagna J, et al. Sci Rep. 2018 Dec 4;8(1):17574. doi: 10.1038/s41598-018-35687-8. Sci Rep. 2018. PMID: 30514854 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

25 results

Search Page

Filters