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362 results

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Page 1
A phase I evaluation of multitargeted antifolate (MTA, LY231514), administered every 21 days, utilizing the modified continual reassessment method for dose escalation.
Rinaldi DA, Kuhn JG, Burris HA, Dorr FA, Rodriguez G, Eckhardt SG, Jones S, Woodworth JR, Baker S, Langley C, Mascorro D, Abrahams T, Von Hoff DD. Rinaldi DA, et al. Among authors: eckhardt sg. Cancer Chemother Pharmacol. 1999;44(5):372-80. doi: 10.1007/s002800050992. Cancer Chemother Pharmacol. 1999. PMID: 10501910 Clinical Trial.
Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer.
Rothenberg ML, Eckardt JR, Kuhn JG, Burris HA 3rd, Nelson J, Hilsenbeck SG, Rodriguez GI, Thurman AM, Smith LS, Eckhardt SG, Weiss GR, Elfring GL, Rinaldi DA, Schaaf LJ, Von Hoff DD. Rothenberg ML, et al. Among authors: eckhardt sg. J Clin Oncol. 1996 Apr;14(4):1128-35. doi: 10.1200/JCO.1996.14.4.1128. J Clin Oncol. 1996. PMID: 8648367 Clinical Trial.
Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks.
Eckhardt SG, Baker SD, Eckardt JR, Burke TG, Warner DL, Kuhn JG, Rodriguez G, Fields S, Thurman A, Smith L, Rothenberg ML, White L, Wissel P, Kunka R, DePee S, Littlefield D, Burris HA, Von Hoff DD, Rowinsky EK. Eckhardt SG, et al. Clin Cancer Res. 1998 Mar;4(3):595-604. Clin Cancer Res. 1998. PMID: 9533526 Clinical Trial.
Phase I trial of paclitaxel and gemcitabine administered every two weeks in patients with refractory solid tumors.
Rothenberg ML, Sharma A, Weiss GR, Villalona-Calero MA, Eckardt JR, Aylesworth C, Kraynak MA, Rinaldi DA, Rodriguez GI, Burris HA 3rd, Eckhardt SG, Stephens CD, Forral K, Nicol SJ, Von Hoff DD. Rothenberg ML, et al. Among authors: eckhardt sg. Ann Oncol. 1998 Jul;9(7):733-8. doi: 10.1023/a:1008286908930. Ann Oncol. 1998. PMID: 9739439 Free article. Clinical Trial.
Phase I and pharmacokinetic study of irofulven, a novel mushroom-derived cytotoxin, administered for five consecutive days every four weeks in patients with advanced solid malignancies.
Eckhardt SG, Baker SD, Britten CD, Hidalgo M, Siu L, Hammond LA, Villalona-Calero MA, Felton S, Drengler R, Kuhn JG, Clark GM, Smith SL, MacDonald JR, Smith C, Moczygemba J, Weitman S, Von Hoff DD, Rowinsky EK. Eckhardt SG, et al. J Clin Oncol. 2000 Dec 15;18(24):4086-97. doi: 10.1200/JCO.2000.18.24.4086. J Clin Oncol. 2000. PMID: 11118470
Phase I dose-finding and pharmacokinetic trial of irinotecan (CPT-11) administered every two weeks.
Rothenberg ML, Kuhn JG, Schaaf LJ, Rodriguez GI, Eckhardt SG, Villalona-Calero MA, Rinaldi DA, Hammond LA, Hodges S, Sharma A, Elfring GL, Petit RG, Locker PK, Miller LL, von Hoff DD. Rothenberg ML, et al. Among authors: eckhardt sg. Ann Oncol. 2001 Nov;12(11):1631-41. doi: 10.1023/a:1013157727506. Ann Oncol. 2001. PMID: 11822765 Free article. Clinical Trial.
A phase I clinical and pharmacokinetic study of the angiogenesis inhibitor, tecogalan sodium.
Eckhardt SG, Burris HA, Eckardt JR, Weiss G, Rodriguez G, Rothenberg M, Rinaldi D, Barrington R, Kuhn JG, Masuo K, Sudo K, Atsumi R, Oguma T, Higashi L, Fields S, Smetzer L, Von Hoff DD. Eckhardt SG, et al. Ann Oncol. 1996 Jul;7(5):491-6. doi: 10.1093/oxfordjournals.annonc.a010638. Ann Oncol. 1996. PMID: 8839904 Free article. Clinical Trial.
362 results