Witvrouw M - Search Results

1

Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4.

Bridger GJ, Skerlj RT, Padmanabhan S, Martellucci SA, Henson GW, Struyf S, Witvrouw M, Schols D, De Clercq E. Bridger GJ, et al. Among authors: witvrouw m. J Med Chem. 1999 Sep 23;42(19):3971-81. doi: 10.1021/jm990211i. J Med Chem. 1999. PMID: 10508445

2

Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibit human immunodeficiency virus replication. 2. Effect of heteroaromatic linkers on the activity of bicyclams.

Bridger GJ, Skerlj RT, Padmanabhan S, Martellucci SA, Henson GW, Abrams MJ, Joao HC, Witvrouw M, De Vreese K, Pauwels R, De Clercq E. Bridger GJ, et al. Among authors: witvrouw m. J Med Chem. 1996 Jan 5;39(1):109-19. doi: 10.1021/jm950584t. J Med Chem. 1996. PMID: 8568797

3

Potent anti-HIV (type 1 and type 2) activity of polyoxometalates: structure-activity relationship and mechanism of action.

Witvrouw M, Weigold H, Pannecouque C, Schols D, De Clercq E, Holan G. Witvrouw M, et al. J Med Chem. 2000 Mar 9;43(5):778-83. doi: 10.1021/jm980263s. J Med Chem. 2000. PMID: 10715146

4

Preparation and anti-HIV activity of O-acylated heparin and dermatan sulfate derivatives with low anticoagulant effect.

Bârzu T, Level M, Petitou M, Lormeau JC, Choay J, Schols D, Baba M, Pauwels R, Witvrouw M, De Clercq E. Bârzu T, et al. Among authors: witvrouw m. J Med Chem. 1993 Nov 12;36(23):3546-55. doi: 10.1021/jm00075a009. J Med Chem. 1993. PMID: 8246223

5

Polyanion inhibitors of human immunodeficiency virus and other viruses. Part 2. Polymerized anionic surfactants derived from amino acids and dipeptides.

Leydet A, El Hachemi H, Boyer B, Lamaty G, Roque JP, Schols D, Snoeck R, Andrei G, Ikeda S, Neyts J, Reymen D, Este J, Witvrouw M, De Clercq E. Leydet A, et al. Among authors: witvrouw m. J Med Chem. 1996 Apr 12;39(8):1626-34. doi: 10.1021/jm950358j. J Med Chem. 1996. PMID: 8648602

6

Novel 1,1,3-trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine derivatives as non-nucleoside reverse transcriptase inhibitors that inhibit human immunodeficiency virus type 1 replication.

Arranz E, Díaz JA, Ingate ST, Witvrouw M, Pannecouque C, Balzarini J, De Clercq E, Vega S. Arranz E, et al. Among authors: witvrouw m. J Med Chem. 1998 Oct 8;41(21):4109-17. doi: 10.1021/jm9802012. J Med Chem. 1998. PMID: 9767646

7

Polyanion inhibitors of HIV and other viruses. 7. Polyanionic compounds and polyzwitterionic compounds derived from cyclodextrins as inhibitors of HIV transmission.

Leydet A, Moullet C, Roque JP, Witvrouw M, Pannecouque C, Andrei G, Snoeck R, Neyts J, Schols D, De Clercq E. Leydet A, et al. Among authors: witvrouw m. J Med Chem. 1998 Dec 3;41(25):4927-32. doi: 10.1021/jm970661f. J Med Chem. 1998. PMID: 9836609

8

Extension of the polyanionic cosalane pharmacophore as a strategy for increasing anti-HIV potency.

Cushman M, Insaf S, Paul G, Ruell JA, De Clercq E, Schols D, Pannecouque C, Witvrouw M, Schaeffer CA, Turpin JA, Williamson K, Rice WG. Cushman M, et al. Among authors: witvrouw m. J Med Chem. 1999 May 20;42(10):1767-77. doi: 10.1021/jm980727m. J Med Chem. 1999. PMID: 10346929

9

New 3'-azido-3'-deoxythymidin-5'-yl O-(omega-hydroxyalkyl) carbonate prodrugs: synthesis and anti-HIV evaluation.

Vlieghe P, Bihel F, Clerc T, Pannecouque C, Witvrouw M, De Clercq E, Salles JP, Chermann JC, Kraus JL. Vlieghe P, et al. Among authors: witvrouw m. J Med Chem. 2001 Mar 1;44(5):777-86. doi: 10.1021/jm001033s. J Med Chem. 2001. PMID: 11262088

10

New 3'-azido-3'-deoxythymidin-5'-yl O-(4-hydroxyalkyl or -alkenyl or -alkylepoxide) carbonate prodrugs: synthesis and anti-HIV evaluation.

Vlieghe P, Clerc T, Pannecouque C, Witvrouw M, De Clercq E, Salles JP, Kraus JL. Vlieghe P, et al. Among authors: witvrouw m. J Med Chem. 2001 Aug 30;44(18):3014-21. doi: 10.1021/jm010863i. J Med Chem. 2001. PMID: 11520210

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