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On the absolute configuration in 1,4-dihydrothiazepine covalent complexes derived from inhibition of class A and C beta-lactamases with 6-methylidene penems.
Mansour TS, Agarwal A, Venkatesan A, Abe T, Mihira A, Takasaki T, Sato K, Ushirogochi H, Yamamura I, Isoda T, Li Z, Yang Y, Kumagai T. Mansour TS, et al. Among authors: yamamura i. ChemMedChem. 2007 Dec;2(12):1713-6. doi: 10.1002/cmdc.200700144. ChemMedChem. 2007. PMID: 17868160 No abstract available.
Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.
Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Yamamura I, Ado M, Tsuyoshi T, Dos Santos O, Gu Y, Sum FW, Li Z, Francisco G, Lin YI, Petersen PJ, Yang Y, Kumagai T, Weiss WJ, Shlaes DM, Knox JR, Mansour TS. Venkatesan AM, et al. Among authors: yamamura i. J Med Chem. 2006 Jul 27;49(15):4623-37. doi: 10.1021/jm060021p. J Med Chem. 2006. PMID: 16854068
A novel, mild, and facile method to prepare 6-methylidene penem derivatives.
Abe T, Sato C, Ushirogochi H, Sato K, Takasaki T, Isoda T, Mihira A, Yamamura I, Hayashi K, Kumagai T, Tamai S, Shiro M, Venkatesan AM, Mansour TS. Abe T, et al. Among authors: yamamura i. J Org Chem. 2004 Sep 3;69(18):5850-60. doi: 10.1021/jo049880g. J Org Chem. 2004. PMID: 15373470
30 results