Horwitz JP - Search Results

1

Preclinical efficacy of thioxanthone SR271425 against transplanted solid tumors of mouse and human origin.

Corbett TH, Panchapor C, Polin L, Lowichik N, Pugh S, White K, Kushner J, Meyer J, Czarnecki J, Chinnukroh S, Edelstein M, LoRusso P, Heilbrun L, Horwitz JP, Grieshaber C, Perni R, Wentland M, Coughlin S, Elenbaas S, Philion R, Rake J. Corbett TH, et al. Among authors: horwitz jp. Invest New Drugs. 1999;17(1):17-27. doi: 10.1023/a:1006267517726. Invest New Drugs. 1999. PMID: 10555119

2

Preclinical efficacy evaluations of XK-469: dose schedule, route and cross-resistance behavior in tumor bearing mice.

Polin L, White K, Kushner J, Paluch J, Simpson C, Pugh S, Edelstein MK, Hazeldine S, Fontana J, LoRusso P, Horwitz JP, Corbett TH. Polin L, et al. Among authors: horwitz jp. Invest New Drugs. 2002 Feb;20(1):13-22. doi: 10.1023/a:1014469828729. Invest New Drugs. 2002. PMID: 12003190

3

Preclinical antitumor efficacy of analogs of XK469: sodium-(2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]propionate.

Corbett TH, LoRusso P, Demchick L, Simpson C, Pugh S, White K, Kushner J, Polin L, Meyer J, Czarnecki J, Heilbrun L, Horwitz JP, Gross JL, Behrens CH, Harrison BA, McRipley RJ, Trainor G. Corbett TH, et al. Among authors: horwitz jp. Invest New Drugs. 1998;16(2):129-39. doi: 10.1023/a:1006174622061. Invest New Drugs. 1998. PMID: 9848576

4

Lack of in vitro-in vivo correlation of a novel investigational anticancer agent, SH 30.

Poondru S, Parchment RE, Purohit V, LoRusso P, Horwitz JP, Hazeldine ST, Polin L, Corbett T, Jasti BR. Poondru S, et al. Among authors: horwitz jp. Invest New Drugs. 2002 Feb;20(1):23-33. doi: 10.1023/a:1014457510073. Invest New Drugs. 2002. PMID: 12003192

5

Part 3: synthesis and biological evaluation of some analogs of the antitumor agents, 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid, and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy}propionic acid.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Biehl J, Horwitz JP. Hazeldine ST, et al. Among authors: horwitz jp. Bioorg Med Chem. 2005 Feb 15;13(4):1069-81. doi: 10.1016/j.bmc.2004.11.034. Bioorg Med Chem. 2005. PMID: 15670915

6

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: horwitz jp. Bioorg Med Chem. 2005 Jun 2;13(12):3910-20. doi: 10.1016/j.bmc.2005.04.011. Bioorg Med Chem. 2005. PMID: 15911307

7

Synthesis and biological evaluation of conformationally constrained analogs of the antitumor agents XK469 and SH80. Part 5.

Hazeldine ST, Polin L, Kushner J, White K, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: horwitz jp. Bioorg Med Chem. 2006 Apr 1;14(7):2462-7. doi: 10.1016/j.bmc.2005.11.036. Epub 2005 Dec 5. Bioorg Med Chem. 2006. PMID: 16337128

8

Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, Paluch J, White K, Edelstein M, Palomino E, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: horwitz jp. J Med Chem. 2001 May 24;44(11):1758-76. doi: 10.1021/jm0005149. J Med Chem. 2001. PMID: 11356111

9

II. Synthesis and biological evaluation of some bioisosteres and congeners of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).

Hazeldine ST, Polin L, Kushner J, White K, Bouregeois NM, Crantz B, Palomino E, Corbett TH, Horwitz JP. Hazeldine ST, et al. Among authors: horwitz jp. J Med Chem. 2002 Jul 4;45(14):3130-7. doi: 10.1021/jm0200097. J Med Chem. 2002. PMID: 12086498

10

Comparative molecular field analysis of the antitumor activity of 9H-thioxanthen-9-one derivatives against pancreatic ductal carcinoma 03.

Horwitz JP, Massova I, Wiese TE, Besler BH, Corbett TH. Horwitz JP, et al. J Med Chem. 1994 Mar 18;37(6):781-6. doi: 10.1021/jm00032a010. J Med Chem. 1994. PMID: 8145227

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