Filpula D - Search Results

1

Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds.

Lee LS, Conover C, Shi C, Whitlow M, Filpula D. Lee LS, et al. Among authors: filpula d. Bioconjug Chem. 1999 Nov-Dec;10(6):973-81. doi: 10.1021/bc990076o. Bioconjug Chem. 1999. PMID: 10563766

2

Controlled release of proteins from their poly(ethylene glycol) conjugates: drug delivery systems employing 1,6-elimination.

Greenwald RB, Yang K, Zhao H, Conover CD, Lee S, Filpula D. Greenwald RB, et al. Among authors: filpula d. Bioconjug Chem. 2003 Mar-Apr;14(2):395-403. doi: 10.1021/bc025652m. Bioconjug Chem. 2003. PMID: 12643750

3

Single-chain Fv with manifold N-glycans as bifunctional scaffolds for immunomolecules.

Wang M, Lee LS, Nepomich A, Yang JD, Conover C, Whitlow M, Filpula D. Wang M, et al. Among authors: filpula d. Protein Eng. 1998 Dec;11(12):1277-83. doi: 10.1093/protein/11.12.1277. Protein Eng. 1998. PMID: 9930678

4

Multivalent Fvs: characterization of single-chain Fv oligomers and preparation of a bispecific Fv.

Whitlow M, Filpula D, Rollence ML, Feng SL, Wood JF. Whitlow M, et al. Among authors: filpula d. Protein Eng. 1994 Aug;7(8):1017-26. doi: 10.1093/protein/7.8.1017. Protein Eng. 1994. PMID: 7809028

5

An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability.

Whitlow M, Bell BA, Feng SL, Filpula D, Hardman KD, Hubert SL, Rollence ML, Wood JF, Schott ME, Milenic DE, et al. Whitlow M, et al. Among authors: filpula d. Protein Eng. 1993 Nov;6(8):989-95. doi: 10.1093/protein/6.8.989. Protein Eng. 1993. PMID: 8309948

6

Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49.

Milenic DE, Yokota T, Filpula DR, Finkelman MA, Dodd SW, Wood JF, Whitlow M, Snoy P, Schlom J. Milenic DE, et al. Among authors: filpula dr. Cancer Res. 1991 Dec 1;51(23 Pt 1):6363-71. Cancer Res. 1991. PMID: 1933899

7

Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation.

Basu A, Yang K, Wang M, Liu S, Chintala R, Palm T, Zhao H, Peng P, Wu D, Zhang Z, Hua J, Hsieh MC, Zhou J, Petti G, Li X, Janjua A, Mendez M, Liu J, Longley C, Zhang Z, Mehlig M, Borowski V, Viswanathan M, Filpula D. Basu A, et al. Among authors: filpula d. Bioconjug Chem. 2006 May-Jun;17(3):618-30. doi: 10.1021/bc050322y. Bioconjug Chem. 2006. PMID: 16704199

8

Releasable PEGylation of mesothelin targeted immunotoxin SS1P achieves single dosage complete regression of a human carcinoma in mice.

Filpula D, Yang K, Basu A, Hassan R, Xiang L, Zhang Z, Wang M, Wang QC, Ho M, Beers R, Zhao H, Peng P, Zhou J, Li X, Petti G, Janjua A, Liu J, Wu D, Yu D, Zhang Z, Longley C, FitzGerald D, Kreitman RJ, Pastan I. Filpula D, et al. Bioconjug Chem. 2007 May-Jun;18(3):773-84. doi: 10.1021/bc060314x. Epub 2007 Mar 9. Bioconjug Chem. 2007. PMID: 17346030

9

Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins.

Zhao H, Yang K, Martinez A, Basu A, Chintala R, Liu HC, Janjua A, Wang M, Filpula D. Zhao H, et al. Among authors: filpula d. Bioconjug Chem. 2006 Mar-Apr;17(2):341-51. doi: 10.1021/bc050270c. Bioconjug Chem. 2006. PMID: 16536464

10

Engineering an arginine catabolizing bioconjugate: Biochemical and pharmacological characterization of PEGylated derivatives of arginine deiminase from Mycoplasma arthritidis.

Wang M, Basu A, Palm T, Hua J, Youngster S, Hwang L, Liu HC, Li X, Peng P, Zhang Y, Zhao H, Zhang Z, Longley C, Mehlig M, Borowski V, Sai P, Viswanathan M, Jang E, Petti G, Liu S, Yang K, Filpula D. Wang M, et al. Among authors: filpula d. Bioconjug Chem. 2006 Nov-Dec;17(6):1447-59. doi: 10.1021/bc060198y. Bioconjug Chem. 2006. PMID: 17105223

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