Obedencio GP - Search Results

1

Involucrin-positive keratinocytes demonstrate decreased migration speed but sustained directional migration in a DC electric field.

Obedencio GP, Nuccitelli R, Isseroff RR. Obedencio GP, et al. J Invest Dermatol. 1999 Nov;113(5):851-855. doi: 10.1046/j.1523-1747.1999.00763.x. J Invest Dermatol. 1999. PMID: 10571745 Free article.

2

Pharmacodynamics of telavancin (TD-6424), a novel bactericidal agent, against gram-positive bacteria.

Hegde SS, Reyes N, Wiens T, Vanasse N, Skinner R, McCullough J, Kaniga K, Pace J, Thomas R, Shaw JP, Obedencio G, Judice JK. Hegde SS, et al. Antimicrob Agents Chemother. 2004 Aug;48(8):3043-50. doi: 10.1128/AAC.48.8.3043-3050.2004. Antimicrob Agents Chemother. 2004. PMID: 15273119 Free PMC article.

3

Gut-Selective Design of Orally Administered Izencitinib (TD-1473) Limits Systemic Exposure and Effects of Janus Kinase Inhibition in Nonclinical Species.

Hardwick RN, Brassil P, Badagnani I, Perkins K, Obedencio GP, Kim AS, Conner MW, Bourdet DL, Harstad EB. Hardwick RN, et al. Among authors: obedencio gp. Toxicol Sci. 2022 Mar 28;186(2):323-337. doi: 10.1093/toxsci/kfac002. Toxicol Sci. 2022. PMID: 35134999 Free PMC article.

4

Discovery of Axelopran (TD-1211): A Peripherally Restricted μ-Opioid Receptor Antagonist.

Long DD, Armstrong SR, Beattie DT, Campbell CB, Church TJ, Colson PJ, Dalziel SM, Jacobsen JR, Jiang L, Obedencio GP, Rapta M, Saito D, Stergiades I, Tsuruda PR, Van Dyke PM, Vickery RG. Long DD, et al. Among authors: obedencio gp. ACS Med Chem Lett. 2019 Nov 26;10(12):1641-1647. doi: 10.1021/acsmedchemlett.9b00406. eCollection 2019 Dec 12. ACS Med Chem Lett. 2019. PMID: 31857840 Free PMC article.

5

Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series of μ-opioid receptor antagonists.

Jiang L, Beattie DT, Jacobsen JR, Kintz S, Obedencio GP, Saito D, Stergiades I, Vickery RG, Long DD. Jiang L, et al. Among authors: obedencio gp. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2926-2930. doi: 10.1016/j.bmcl.2017.04.092. Epub 2017 May 3. Bioorg Med Chem Lett. 2017. PMID: 28499731

6

Preclinical to clinical translation of CNS transporter occupancy of TD-9855, a novel norepinephrine and serotonin reuptake inhibitor.

Smith JA, Bourdet DL, Daniels OT, Ding YS, Gallezot JD, Henry S, Kim KH, Kshirsagar S, Martin WJ, Obedencio GP, Stangeland E, Tsuruda PR, Williams W, Carson RE, Patil ST. Smith JA, et al. Among authors: obedencio gp. Int J Neuropsychopharmacol. 2014 Dec 13;18(2):pyu027. doi: 10.1093/ijnp/pyu027. Int J Neuropsychopharmacol. 2014. PMID: 25522383 Free PMC article.

7

Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model.

Shen F, Tsuruda PR, Smith JA, Obedencio GP, Martin WJ. Shen F, et al. Among authors: obedencio gp. PLoS One. 2013 Sep 30;8(9):e74891. doi: 10.1371/journal.pone.0074891. eCollection 2013. PLoS One. 2013. PMID: 24098676 Free PMC article.

8

In vivo pharmacological characterization of TD-4208, a novel lung-selective inhaled muscarinic antagonist with sustained bronchoprotective effect in experimental animal models.

Pulido-Rios MT, McNamara A, Obedencio GP, Ji Y, Jaw-Tsai S, Martin WJ, Hegde SS. Pulido-Rios MT, et al. Among authors: obedencio gp. J Pharmacol Exp Ther. 2013 Aug;346(2):241-50. doi: 10.1124/jpet.113.203554. Epub 2013 May 17. J Pharmacol Exp Ther. 2013. PMID: 23685545

9

Prediction of human serotonin and norepinephrine transporter occupancy of duloxetine by pharmacokinetic/pharmacodynamic modeling in the rat.

Bourdet DL, Tsuruda PR, Obedencio GP, Smith JA. Bourdet DL, et al. Among authors: obedencio gp. J Pharmacol Exp Ther. 2012 Apr;341(1):137-45. doi: 10.1124/jpet.111.188417. Epub 2012 Jan 10. J Pharmacol Exp Ther. 2012. PMID: 22235148

10

5-HT(4) receptor agonist mediated enhancement of cognitive function in vivo and amyloid precursor protein processing in vitro: A pharmacodynamic and pharmacokinetic assessment.

Shen F, Smith JA, Chang R, Bourdet DL, Tsuruda PR, Obedencio GP, Beattie DT. Shen F, et al. Among authors: obedencio gp. Neuropharmacology. 2011 Jul-Aug;61(1-2):69-79. doi: 10.1016/j.neuropharm.2011.02.026. Epub 2011 Mar 12. Neuropharmacology. 2011. PMID: 21392515

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