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The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
Jacotot E, Ravagnan L, Loeffler M, Ferri KF, Vieira HL, Zamzami N, Costantini P, Druillennec S, Hoebeke J, Briand JP, Irinopoulou T, Daugas E, Susin SA, Cointe D, Xie ZH, Reed JC, Roques BP, Kroemer G. Jacotot E, et al. Among authors: hoebeke j. J Exp Med. 2000 Jan 3;191(1):33-46. doi: 10.1084/jem.191.1.33. J Exp Med. 2000. PMID: 10620603 Free PMC article.
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.
Jacotot E, Ferri KF, El Hamel C, Brenner C, Druillennec S, Hoebeke J, Rustin P, Métivier D, Lenoir C, Geuskens M, Vieira HL, Loeffler M, Belzacq AS, Briand JP, Zamzami N, Edelman L, Xie ZH, Reed JC, Roques BP, Kroemer G. Jacotot E, et al. Among authors: hoebeke j. J Exp Med. 2001 Feb 19;193(4):509-19. doi: 10.1084/jem.193.4.509. J Exp Med. 2001. PMID: 11181702 Free PMC article.
Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells.
Borgne-Sanchez A, Dupont S, Langonné A, Baux L, Lecoeur H, Chauvier D, Lassalle M, Déas O, Brière JJ, Brabant M, Roux P, Péchoux C, Briand JP, Hoebeke J, Deniaud A, Brenner C, Rustin P, Edelman L, Rebouillat D, Jacotot E. Borgne-Sanchez A, et al. Among authors: hoebeke j. Cell Death Differ. 2007 Mar;14(3):422-35. doi: 10.1038/sj.cdd.4402018. Epub 2006 Aug 4. Cell Death Differ. 2007. PMID: 16888644
255 results