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The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
Jacotot E, Ravagnan L, Loeffler M, Ferri KF, Vieira HL, Zamzami N, Costantini P, Druillennec S, Hoebeke J, Briand JP, Irinopoulou T, Daugas E, Susin SA, Cointe D, Xie ZH, Reed JC, Roques BP, Kroemer G. Jacotot E, et al. Among authors: irinopoulou t. J Exp Med. 2000 Jan 3;191(1):33-46. doi: 10.1084/jem.191.1.33. J Exp Med. 2000. PMID: 10620603 Free PMC article.
Two distinct pathways leading to nuclear apoptosis.
Susin SA, Daugas E, Ravagnan L, Samejima K, Zamzami N, Loeffler M, Costantini P, Ferri KF, Irinopoulou T, Prévost MC, Brothers G, Mak TW, Penninger J, Earnshaw WC, Kroemer G. Susin SA, et al. Among authors: irinopoulou t. J Exp Med. 2000 Aug 21;192(4):571-80. doi: 10.1084/jem.192.4.571. J Exp Med. 2000. PMID: 10952727 Free PMC article.
55 results