Challis BG - Search Results

1

The role of melanocortin signalling in the control of body weight: evidence from human and murine genetic models.

Yeo GS, Farooqi IS, Challis BG, Jackson RS, O'Rahilly S. Yeo GS, et al. Among authors: challis bg. QJM. 2000 Jan;93(1):7-14. doi: 10.1093/qjmed/93.1.7. QJM. 2000. PMID: 10623776 Review.

2

The CART gene and human obesity: mutational analysis and population genetics.

Challis BG, Yeo GS, Farooqi IS, Luan J, Aminian S, Halsall DJ, Keogh JM, Wareham NJ, O'Rahilly S. Challis BG, et al. Diabetes. 2000 May;49(5):872-5. doi: 10.2337/diabetes.49.5.872. Diabetes. 2000. PMID: 10905499

3

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism.

Challis BG, Pritchard LE, Creemers JW, Delplanque J, Keogh JM, Luan J, Wareham NJ, Yeo GS, Bhattacharyya S, Froguel P, White A, Farooqi IS, O'Rahilly S. Challis BG, et al. Hum Mol Genet. 2002 Aug 15;11(17):1997-2004. doi: 10.1093/hmg/11.17.1997. Hum Mol Genet. 2002. PMID: 12165561

4

Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms.

Yeo GS, Lank EJ, Farooqi IS, Keogh J, Challis BG, O'Rahilly S. Yeo GS, et al. Among authors: challis bg. Hum Mol Genet. 2003 Mar 1;12(5):561-74. doi: 10.1093/hmg/ddg057. Hum Mol Genet. 2003. PMID: 12588803

5

Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population.

Bhattacharyya S, Luan J, Challis B, Schmitz C, Clarkson P, Franks PW, Middelberg R, Keogh J, Farooqi IS, Montague C, Brennand J, Wareham NJ, O'Rahilly S. Bhattacharyya S, et al. Diabetes. 2003 May;52(5):1296-9. doi: 10.2337/diabetes.52.5.1296. Diabetes. 2003. PMID: 12716769

6

Minireview: human obesity-lessons from monogenic disorders.

O'Rahilly S, Farooqi IS, Yeo GS, Challis BG. O'Rahilly S, et al. Among authors: challis bg. Endocrinology. 2003 Sep;144(9):3757-64. doi: 10.1210/en.2003-0373. Endocrinology. 2003. PMID: 12933645 Review.

7

Acute effects of PYY3-36 on food intake and hypothalamic neuropeptide expression in the mouse.

Challis BG, Pinnock SB, Coll AP, Carter RN, Dickson SL, O'Rahilly S. Challis BG, et al. Biochem Biophys Res Commun. 2003 Nov 28;311(4):915-9. doi: 10.1016/j.bbrc.2003.10.089. Biochem Biophys Res Commun. 2003. PMID: 14623268

8

Association between physical activity and blood pressure is modified by variants in the G-protein coupled receptor 10.

Franks PW, Bhattacharyya S, Luan J, Montague C, Brennand J, Challis B, Brage S, Ekelund U, Middelberg RP, O'Rahilly S, Wareham NJ. Franks PW, et al. Hypertension. 2004 Feb;43(2):224-8. doi: 10.1161/01.HYP.0000109319.63240.08. Epub 2003 Dec 22. Hypertension. 2004. PMID: 14691196

9

Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.

Challis BG, Luan J, Keogh J, Wareham NJ, Farooqi IS, O'Rahilly S. Challis BG, et al. Int J Obes Relat Metab Disord. 2004 Mar;28(3):442-6. doi: 10.1038/sj.ijo.0802564. Int J Obes Relat Metab Disord. 2004. PMID: 14724656

10

Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36).

Challis BG, Coll AP, Yeo GS, Pinnock SB, Dickson SL, Thresher RR, Dixon J, Zahn D, Rochford JJ, White A, Oliver RL, Millington G, Aparicio SA, Colledge WH, Russ AP, Carlton MB, O'Rahilly S. Challis BG, et al. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4695-700. doi: 10.1073/pnas.0306931101. Epub 2004 Mar 15. Proc Natl Acad Sci U S A. 2004. PMID: 15070780 Free PMC article.

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