Perego R - Search Results

1

Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.

Visco C, Magistrelli G, Bosotti R, Perego R, Rusconi L, Toma S, Zamai M, Acuto O, Isacchi A. Visco C, et al. Among authors: perego r. Biochemistry. 2000 Mar 14;39(10):2784-91. doi: 10.1021/bi991840x. Biochemistry. 2000. PMID: 10704231

2

Regulation of the wild-type and Y1235D mutant Met kinase activation.

Cristiani C, Rusconi L, Perego R, Schiering N, Kalisz HM, Knapp S, Isacchi A. Cristiani C, et al. Among authors: perego r. Biochemistry. 2005 Nov 1;44(43):14110-9. doi: 10.1021/bi051242k. Biochemistry. 2005. PMID: 16245927

3

Role of the Src homology 2 domains and interdomain regions in ZAP-70 phosphorylation and enzymatic activity.

Magistrelli G, Bosotti R, Valsasina B, Visco C, Perego R, Toma S, Acuto O, Isacchi A. Magistrelli G, et al. Among authors: perego r. Eur J Biochem. 1999 Dec;266(3):1166-73. doi: 10.1046/j.1432-1327.1999.00973.x. Eur J Biochem. 1999. PMID: 10583414 Free article.

4

Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a.

Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Schiering N, et al. Among authors: perego r. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. doi: 10.1073/pnas.1734128100. Epub 2003 Oct 14. Proc Natl Acad Sci U S A. 2003. PMID: 14559966 Free PMC article.

5

Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays.

Troiani S, Lupi R, Perego R, Depaolini SR, Thieffine S, Bosotti R, Rusconi L. Troiani S, et al. Among authors: perego r. FEBS J. 2011 Oct;278(19):3676-87. doi: 10.1111/j.1742-4658.2011.08286.x. Epub 2011 Sep 6. FEBS J. 2011. PMID: 21812934 Free article.

6

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.

Papeo G, Posteri H, Borghi D, Busel AA, Caprera F, Casale E, Ciomei M, Cirla A, Corti E, D'Anello M, Fasolini M, Forte B, Galvani A, Isacchi A, Khvat A, Krasavin MY, Lupi R, Orsini P, Perego R, Pesenti E, Pezzetta D, Rainoldi S, Riccardi-Sirtori F, Scolaro A, Sola F, Zuccotto F, Felder ER, Donati D, Montagnoli A. Papeo G, et al. Among authors: perego r. J Med Chem. 2015 Sep 10;58(17):6875-98. doi: 10.1021/acs.jmedchem.5b00680. Epub 2015 Aug 26. J Med Chem. 2015. PMID: 26222319

7

Identification of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as a new class of orally and selective Polo-like kinase 1 inhibitors.

Beria I, Ballinari D, Bertrand JA, Borghi D, Bossi RT, Brasca MG, Cappella P, Caruso M, Ceccarelli W, Ciavolella A, Cristiani C, Croci V, De Ponti A, Fachin G, Ferguson RD, Lansen J, Moll JK, Pesenti E, Posteri H, Perego R, Rocchetti M, Storici P, Volpi D, Valsasina B. Beria I, et al. Among authors: perego r. J Med Chem. 2010 May 13;53(9):3532-51. doi: 10.1021/jm901713n. J Med Chem. 2010. PMID: 20397705

8

High-throughput NMR-based screening with competition binding experiments.

Dalvit C, Flocco M, Knapp S, Mostardini M, Perego R, Stockman BJ, Veronesi M, Varasi M. Dalvit C, et al. Among authors: perego r. J Am Chem Soc. 2002 Jul 3;124(26):7702-9. doi: 10.1021/ja020174b. J Am Chem Soc. 2002. PMID: 12083923

9

Insights into PARP Inhibitors' Selectivity Using Fluorescence Polarization and Surface Plasmon Resonance Binding Assays.

Papeo G, Avanzi N, Bettoni S, Leone A, Paolucci M, Perego R, Quartieri F, Riccardi-Sirtori F, Thieffine S, Montagnoli A, Lupi R. Papeo G, et al. Among authors: perego r. J Biomol Screen. 2014 Sep;19(8):1212-9. doi: 10.1177/1087057114538319. Epub 2014 Jun 10. J Biomol Screen. 2014. PMID: 24916412

10

Impairment of Renal and Hematopoietic Stem/Progenitor Cell Compartments in Frailty Syndrome: Link With Oxidative Stress, Plasma Cytokine Profiles, and Nuclear DNA Damage.

Bombelli S, Grasselli C, Mazzola P, Veronesi V, Morabito I, Zucchini N, Scollo CM, Blanco SI, De Marco S, Torsello B, Vitarelli F, Antolini L, Bianchi C, Leoni V, Bellelli G, Perego RA. Bombelli S, et al. Among authors: perego ra. J Gerontol A Biol Sci Med Sci. 2024 Nov 1;79(11):glae188. doi: 10.1093/gerona/glae188. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39066510 Free PMC article.

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