Maly DJ - Search Results

1

Combinatorial target-guided ligand assembly: identification of potent subtype-selective c-Src inhibitors.

Maly DJ, Choong IC, Ellman JA. Maly DJ, et al. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2419-24. doi: 10.1073/pnas.97.6.2419. Proc Natl Acad Sci U S A. 2000. PMID: 10716979 Free PMC article.

2

A chemically controlled Cas9 switch enables temporal modulation of diverse effectors.

Wei CT, Popp NA, Peleg O, Powell RL, Borenstein E, Maly DJ, Fowler DM. Wei CT, et al. Among authors: maly dj. Nat Chem Biol. 2023 Aug;19(8):981-991. doi: 10.1038/s41589-023-01278-6. Epub 2023 Mar 6. Nat Chem Biol. 2023. PMID: 36879061 Free PMC article.

3

Molecular determinants of Hsp90 dependence of Src kinase revealed by deep mutational scanning.

Nguyen V, Ahler E, Sitko KA, Stephany JJ, Maly DJ, Fowler DM. Nguyen V, et al. Among authors: maly dj. Protein Sci. 2023 Jul;32(7):e4656. doi: 10.1002/pro.4656. Protein Sci. 2023. PMID: 37167432 Free PMC article.

4

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

Golkowski M, Lius A, Sapre T, Lau HT, Moreno T, Maly DJ, Ong SE. Golkowski M, et al. Among authors: maly dj. Mol Cell. 2023 Mar 2;83(5):803-818.e8. doi: 10.1016/j.molcel.2023.01.015. Epub 2023 Feb 2. Mol Cell. 2023. PMID: 36736316 Free PMC article.

5

Altered substrate specificity of drug-resistant human immunodeficiency virus type 1 protease.

Dauber DS, Ziermann R, Parkin N, Maly DJ, Mahrus S, Harris JL, Ellman JA, Petropoulos C, Craik CS. Dauber DS, et al. Among authors: maly dj. J Virol. 2002 Feb;76(3):1359-68. doi: 10.1128/jvi.76.3.1359-1368.2002. J Virol. 2002. PMID: 11773410 Free PMC article.

6

Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly.

Kehoe JW, Maly DJ, Verdugo DE, Armstrong JI, Cook BN, Ouyang YB, Moore KL, Ellman JA, Bertozzi CR. Kehoe JW, et al. Among authors: maly dj. Bioorg Med Chem Lett. 2002 Feb 11;12(3):329-32. doi: 10.1016/s0960-894x(01)00744-2. Bioorg Med Chem Lett. 2002. PMID: 11814789

7

Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore.

Maly DJ, Leonetti F, Backes BJ, Dauber DS, Harris JL, Craik CS, Ellman JA. Maly DJ, et al. J Org Chem. 2002 Feb 8;67(3):910-5. doi: 10.1021/jo016140o. J Org Chem. 2002. PMID: 11856036

8

Peptide microarrays for the determination of protease substrate specificity.

Salisbury CM, Maly DJ, Ellman JA. Salisbury CM, et al. Among authors: maly dj. J Am Chem Soc. 2002 Dec 18;124(50):14868-70. doi: 10.1021/ja027477q. J Am Chem Soc. 2002. PMID: 12475327

9

Profiling serine protease substrate specificity with solution phase fluorogenic peptide microarrays.

Gosalia DN, Salisbury CM, Maly DJ, Ellman JA, Diamond SL. Gosalia DN, et al. Among authors: maly dj. Proteomics. 2005 Apr;5(5):1292-8. doi: 10.1002/pmic.200401011. Proteomics. 2005. PMID: 15742319

10

Combinatorial strategies for targeting protein families: application to the proteases.

Maly DJ, Huang L, Ellman JA. Maly DJ, et al. Chembiochem. 2002 Jan 4;3(1):16-37. doi: 10.1002/1439-7633(20020104)3:1<16::AID-CBIC16>3.0.CO;2-Z. Chembiochem. 2002. PMID: 17590950

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