Houghton PJ - Search Results

1

Pharmacokinetics of irinotecan and its metabolites SN-38 and APC in children with recurrent solid tumors after protracted low-dose irinotecan.

Ma MK, Zamboni WC, Radomski KM, Furman WL, Santana VM, Houghton PJ, Hanna SK, Smith AK, Stewart CF. Ma MK, et al. Among authors: houghton pj. Clin Cancer Res. 2000 Mar;6(3):813-9. Clin Cancer Res. 2000. PMID: 10741701 Clinical Trial.

2

Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors.

Houghton PJ, Cheshire PJ, Myers L, Stewart CF, Synold TW, Houghton JA. Houghton PJ, et al. Among authors: houghton ja. Cancer Chemother Pharmacol. 1992;31(3):229-39. doi: 10.1007/BF00685553. Cancer Chemother Pharmacol. 1992. PMID: 1464161

3

Accumulation, intracellular metabolism, and antitumor activity of high- and low-dose methotrexate in human osteosarcoma xenografts.

Meyer WH, Loftin SK, Houghton JA, Houghton PJ. Meyer WH, et al. Among authors: houghton ja, houghton pj. Cancer Commun. 1990;2(6):219-29. doi: 10.3727/095535490820874407. Cancer Commun. 1990. PMID: 1696116

4

Efficacy, toxicity, pharmacokinetics, and in vitro metabolism of the enantiomers of ifosfamide in mice.

Masurel D, Houghton PJ, Young CL, Wainer IW. Masurel D, et al. Among authors: houghton pj. Cancer Res. 1990 Jan 15;50(2):252-5. Cancer Res. 1990. PMID: 2295063

5

N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)urea, a novel agent equally cytotoxic to nonproliferating human colon adenocarcinoma cells.

Houghton PJ, Bailey FC, Germain GS, Grindey GB, Witt BC, Houghton JA. Houghton PJ, et al. Among authors: houghton ja. Cancer Res. 1990 Jan 15;50(2):318-22. Cancer Res. 1990. PMID: 2295071

6

Influence of dose of [6RS]leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts.

Houghton JA, Williams LG, Cheshire PJ, Wainer IW, Jadaud P, Houghton PJ. Houghton JA, et al. Among authors: houghton pj. Cancer Res. 1990 Jul 1;50(13):3940-6. Cancer Res. 1990. PMID: 2354443

7

Phase II testing of melphalan in children with newly diagnosed rhabdomyosarcoma: a model for anticancer drug development.

Horowitz ME, Etcubanas E, Christensen ML, Houghton JA, George SL, Green AA, Houghton PJ. Horowitz ME, et al. Among authors: houghton ja, houghton pj. J Clin Oncol. 1988 Feb;6(2):308-14. doi: 10.1200/JCO.1988.6.2.308. J Clin Oncol. 1988. PMID: 3276826 Clinical Trial.

8

Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors.

Houghton PJ, Cheshire PJ, Hallman JD 2nd, Lutz L, Friedman HS, Danks MK, Houghton JA. Houghton PJ, et al. Among authors: houghton ja. Cancer Chemother Pharmacol. 1995;36(5):393-403. doi: 10.1007/BF00686188. Cancer Chemother Pharmacol. 1995. PMID: 7634381

9

Therapeutic efficacy of the topoisomerase I inhibitor 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptothecin against human tumor xenografts: lack of cross-resistance in vivo in tumors with acquired resistance to the topoisomerase I inhibitor 9-dimethylaminomethyl-10-hydroxycamptothecin.

Houghton PJ, Cheshire PJ, Hallman JC, Bissery MC, Mathieu-Boué A, Houghton JA. Houghton PJ, et al. Among authors: houghton ja. Cancer Res. 1993 Jun 15;53(12):2823-9. Cancer Res. 1993. PMID: 8504425

10

Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations.

Beck WT, Grogan TM, Willman CL, Cordon-Cardo C, Parham DM, Kuttesch JF, Andreeff M, Bates SE, Berard CW, Boyett JM, Brophy NA, Broxterman HJ, Chan HS, Dalton WS, Dietel M, Fojo AT, Gascoyne RD, Head D, Houghton PJ, Srivastava DK, Lehnert M, Leith CP, Paietta E, Pavelic ZP, Weinstein R. Beck WT, et al. Among authors: houghton pj. Cancer Res. 1996 Jul 1;56(13):3010-20. Cancer Res. 1996. PMID: 8674056 Review.

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