Hugen PW - Search Results

1

Carbamazepine--indinavir interaction causes antiretroviral therapy failure.

Hugen PW, Burger DM, Brinkman K, ter Hofstede HJ, Schuurman R, Koopmans PP, Hekster YA. Hugen PW, et al. Ann Pharmacother. 2000 Apr;34(4):465-70. doi: 10.1345/aph.19211. Ann Pharmacother. 2000. PMID: 10772431

2

The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy volunteers.

Aarnoutse RE, Grintjes KJ, Telgt DS, Stek M Jr, Hugen PW, Reiss P, Koopmans PP, Hekster YA, Burger DM. Aarnoutse RE, et al. Among authors: hugen pw. Clin Pharmacol Ther. 2002 Jan;71(1):57-67. doi: 10.1067/mcp.2002.121424. Clin Pharmacol Ther. 2002. PMID: 11823758 Clinical Trial.

3

Pros and cons of therapeutic drug monitoring of antiretroviral agents.

Burger DM, Aarnoutse RE, Hugen PW. Burger DM, et al. Among authors: hugen pw. Curr Opin Infect Dis. 2002 Feb;15(1):17-22. doi: 10.1097/00001432-200202000-00004. Curr Opin Infect Dis. 2002. PMID: 11964901

4

Simultaneous determination of the HIV-protease inhibitors indinavir, nelfinavir, saquinavir and ritonavir in human plasma by reversed-phase high-performance liquid chromatography.

Hugen PW, Verweij-van Wissen CP, Burger DM, Wuis EW, Koopmans PP, Hekster YA. Hugen PW, et al. J Chromatogr B Biomed Sci Appl. 1999 Apr 30;727(1-2):139-49. doi: 10.1016/s0378-4347(99)00079-1. J Chromatogr B Biomed Sci Appl. 1999. PMID: 10360433

5

Low plasma concentrations of indinavir are related to virological treatment failure in HIV-1-infected patients on indinavir-containing triple therapy.

Burger DM, Hoetelmans RM, Hugen PW, Mulder JW, Meenhorst PL, Koopmans PP, Brinkman K, Keuter M, Dolmans W, Hekster YA. Burger DM, et al. Among authors: hugen pw. Antivir Ther. 1998;3(4):215-20. Antivir Ther. 1998. PMID: 10682141

6

Development of an indinavir oral liquid for children.

Hugen PW, Burger DM, ter Hofstede HJ, Koopmans PP, Hekster YA. Hugen PW, et al. Am J Health Syst Pharm. 2000 Jul 15;57(14):1332-9. doi: 10.1093/ajhp/57.14.1332. Am J Health Syst Pharm. 2000. PMID: 10918923 Clinical Trial.

7

Saliva as a specimen for monitoring compliance but not for predicting plasma concentrations in patients with HIV treated with indinavir.

Hugen PW, Burger DM, de Graaff M, ter Hofstede HJ, Hoetelmans RM, Brinkman K, Meenhorst PL, Mulder JW, Koopmans PP, Hekster YA. Hugen PW, et al. Ther Drug Monit. 2000 Aug;22(4):437-45. doi: 10.1097/00007691-200008000-00013. Ther Drug Monit. 2000. PMID: 10942185

8

Dose-finding study of a once-daily indinavir/ritonavir regimen.

Hugen PW, Burger DM, ter Hofstede HJ, Koopmans PP, Stek M, Hekster YA, Reiss P, Lange JM. Hugen PW, et al. J Acquir Immune Defic Syndr. 2000 Nov 1;25(3):236-45. doi: 10.1097/00126334-200011010-00005. J Acquir Immune Defic Syndr. 2000. PMID: 11115954 Clinical Trial.

9

Saquinavir soft-gel capsules (Fortovase) give lower exposure than expected, even after a high-fat breakfast.

Hugen PW, Burger DM, Koopmans PP, Stuart JW, Kroon FP, van Leusen R, Hekster YA. Hugen PW, et al. Pharm World Sci. 2002 Jun;24(3):83-6. doi: 10.1023/a:1016121100568. Pharm World Sci. 2002. PMID: 12136744

10

Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice?

Antiretroviral Therapy Cohort Collaboration (ART-CC); Mugavero MJ, May M, Harris R, Saag MS, Costagliola D, Egger M, Phillips A, Günthard HF, Dabis F, Hogg R, de Wolf F, Fatkenheuer G, Gill MJ, Justice A, D'Arminio Monforte A, Lampe F, Miró JM, Staszewski S, Sterne JA. Antiretroviral Therapy Cohort Collaboration (ART-CC), et al. AIDS. 2008 Nov 30;22(18):2481-92. doi: 10.1097/QAD.0b013e328318f130. AIDS. 2008. PMID: 19005271 Free PMC article.

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