Lees JA - Search Results

1

Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors.

Gimm O, Perren A, Weng LP, Marsh DJ, Yeh JJ, Ziebold U, Gil E, Hinze R, Delbridge L, Lees JA, Mutter GL, Robinson BG, Komminoth P, Dralle H, Eng C. Gimm O, et al. Among authors: lees ja. Am J Pathol. 2000 May;156(5):1693-700. doi: 10.1016/S0002-9440(10)65040-7. Am J Pathol. 2000. PMID: 10793080 Free PMC article.

2

PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.

Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C. Weng LP, et al. Among authors: lees ja. Cancer Res. 1999 Nov 15;59(22):5808-14. Cancer Res. 1999. PMID: 10582703

3

Expression of the PTEN tumour suppressor protein during human development.

Gimm O, Attié-Bitach T, Lees JA, Vekemans M, Eng C. Gimm O, et al. Among authors: lees ja. Hum Mol Genet. 2000 Jul 1;9(11):1633-9. doi: 10.1093/hmg/9.11.1633. Hum Mol Genet. 2000. PMID: 10861290

4

Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells.

Perren A, Komminoth P, Saremaslani P, Matter C, Feurer S, Lees JA, Heitz PU, Eng C. Perren A, et al. Among authors: lees ja. Am J Pathol. 2000 Oct;157(4):1097-103. doi: 10.1016/S0002-9440(10)64624-X. Am J Pathol. 2000. PMID: 11021813 Free PMC article.

5

Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast.

Perren A, Weng LP, Boag AH, Ziebold U, Thakore K, Dahia PL, Komminoth P, Lees JA, Mulligan LM, Mutter GL, Eng C. Perren A, et al. Among authors: lees ja. Am J Pathol. 1999 Oct;155(4):1253-60. doi: 10.1016/S0002-9440(10)65227-3. Am J Pathol. 1999. PMID: 10514407 Free PMC article.

6

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers.

Mutter GL, Lin MC, Fitzgerald JT, Kum JB, Baak JP, Lees JA, Weng LP, Eng C. Mutter GL, et al. Among authors: lees ja. J Natl Cancer Inst. 2000 Jun 7;92(11):924-30. doi: 10.1093/jnci/92.11.924. J Natl Cancer Inst. 2000. PMID: 10841828

7

Regulation of the insulin-like developmental pathway of Caenorhabditis elegans by a homolog of the PTEN tumor suppressor gene.

Gil EB, Malone Link E, Liu LX, Johnson CD, Lees JA. Gil EB, et al. Among authors: lees ja. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2925-30. doi: 10.1073/pnas.96.6.2925. Proc Natl Acad Sci U S A. 1999. PMID: 10077613 Free PMC article.

8

E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas.

Ziebold U, Lee EY, Bronson RT, Lees JA. Ziebold U, et al. Among authors: lees ja. Mol Cell Biol. 2003 Sep;23(18):6542-52. doi: 10.1128/MCB.23.18.6542-6552.2003. Mol Cell Biol. 2003. PMID: 12944480 Free PMC article.

9

E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos.

Ziebold U, Reza T, Caron A, Lees JA. Ziebold U, et al. Among authors: lees ja. Genes Dev. 2001 Feb 15;15(4):386-91. doi: 10.1101/gad.858801. Genes Dev. 2001. PMID: 11230146 Free PMC article.

10

Mutant mouse models reveal the relative roles of E2F1 and E2F3 in vivo.

Cloud JE, Rogers C, Reza TL, Ziebold U, Stone JR, Picard MH, Caron AM, Bronson RT, Lees JA. Cloud JE, et al. Among authors: lees ja. Mol Cell Biol. 2002 Apr;22(8):2663-72. doi: 10.1128/MCB.22.8.2663-2672.2002. Mol Cell Biol. 2002. PMID: 11909960 Free PMC article.

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