Wang R - Search Results

1

Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage.

Murphy MP, Uljon SN, Fraser PE, Fauq A, Lookingbill HA, Findlay KA, Smith TE, Lewis PA, McLendon DC, Wang R, Golde TE. Murphy MP, et al. Among authors: wang r. J Biol Chem. 2000 Aug 25;275(34):26277-84. doi: 10.1074/jbc.M002812200. J Biol Chem. 2000. PMID: 10816583 Free article.

2

gamma-Secretase, evidence for multiple proteolytic activities and influence of membrane positioning of substrate on generation of amyloid beta peptides of varying length.

Murphy MP, Hickman LJ, Eckman CB, Uljon SN, Wang R, Golde TE. Murphy MP, et al. Among authors: wang r. J Biol Chem. 1999 Apr 23;274(17):11914-23. doi: 10.1074/jbc.274.17.11914. J Biol Chem. 1999. PMID: 10207012 Free article.

3

Cell-free assays for gamma-secretase activity.

McLendon C, Xin T, Ziani-Cherif C, Murphy MP, Findlay KA, Lewis PA, Pinnix I, Sambamurti K, Wang R, Fauq A, Golde TE. McLendon C, et al. Among authors: wang r. FASEB J. 2000 Dec;14(15):2383-6. doi: 10.1096/fj.00-0286fje. FASEB J. 2000. PMID: 11024004

4

An empirical model of gamma-secretase activity.

Murphy MP, Wang R, Fraser PE, Fauq A, Golde TE. Murphy MP, et al. Among authors: wang r. Ann N Y Acad Sci. 2000;920:233-40. doi: 10.1111/j.1749-6632.2000.tb06928.x. Ann N Y Acad Sci. 2000. PMID: 11193156

5

Amyloid phenotype characterization of transgenic mice overexpressing both mutant amyloid precursor protein and mutant presenilin 1 transgenes.

McGowan E, Sanders S, Iwatsubo T, Takeuchi A, Saido T, Zehr C, Yu X, Uljon S, Wang R, Mann D, Dickson D, Duff K. McGowan E, et al. Among authors: wang r. Neurobiol Dis. 1999 Aug;6(4):231-44. doi: 10.1006/nbdi.1999.0243. Neurobiol Dis. 1999. PMID: 10448051

6

Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides.

Lewis PA, Piper S, Baker M, Onstead L, Murphy MP, Hardy J, Wang R, McGowan E, Golde TE. Lewis PA, et al. Among authors: wang r. Biochim Biophys Acta. 2001 Jul 27;1537(1):58-62. doi: 10.1016/s0925-4439(01)00054-0. Biochim Biophys Acta. 2001. PMID: 11476963 Free article.

7

Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein.

Lichtenthaler SF, Wang R, Grimm H, Uljon SN, Masters CL, Beyreuther K. Lichtenthaler SF, et al. Among authors: wang r. Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3053-8. doi: 10.1073/pnas.96.6.3053. Proc Natl Acad Sci U S A. 1999. PMID: 10077635 Free PMC article.

8

Characterization of a presenilin-mediated amyloid precursor protein carboxyl-terminal fragment gamma. Evidence for distinct mechanisms involved in gamma -secretase processing of the APP and Notch1 transmembrane domains.

Yu C, Kim SH, Ikeuchi T, Xu H, Gasparini L, Wang R, Sisodia SS. Yu C, et al. Among authors: wang r. J Biol Chem. 2001 Nov 23;276(47):43756-60. doi: 10.1074/jbc.C100410200. Epub 2001 Oct 2. J Biol Chem. 2001. PMID: 11583985 Free article.

9

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity.

Weggen S, Eriksen JL, Das P, Sagi SA, Wang R, Pietrzik CU, Findlay KA, Smith TE, Murphy MP, Bulter T, Kang DE, Marquez-Sterling N, Golde TE, Koo EH. Weggen S, et al. Among authors: wang r. Nature. 2001 Nov 8;414(6860):212-6. doi: 10.1038/35102591. Nature. 2001. PMID: 11700559

10

Modulation of A(beta) peptides by estrogen in mouse models.

Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K. Zheng H, et al. Among authors: wang r. J Neurochem. 2002 Jan;80(1):191-6. doi: 10.1046/j.0022-3042.2001.00690.x. J Neurochem. 2002. PMID: 11796757 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

41,823 results

Search Page

Filters