Qiu X - Search Results

1

Crystallization of Escherichia coli beta-ketoacyl-ACP synthase III and the use of a dry flash-cooling technique for data collection.

Janson CA, Konstantinidis AK, Lonsdale JT, Qiu X. Janson CA, et al. Among authors: qiu x. Acta Crystallogr D Biol Crystallogr. 2000 Jun;56(Pt 6):747-8. doi: 10.1107/s0907444900004868. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10818351

2

Structure of apo acyl carrier protein and a proposal to engineer protein crystallization through metal ions.

Qiu X, Janson CA. Qiu X, et al. Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1545-54. doi: 10.1107/S0907444904015422. Epub 2004 Aug 26. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15333924

3

Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus.

Qiu X, Choudhry AE, Janson CA, Grooms M, Daines RA, Lonsdale JT, Khandekar SS. Qiu X, et al. Protein Sci. 2005 Aug;14(8):2087-94. doi: 10.1110/ps.051501605. Epub 2005 Jun 29. Protein Sci. 2005. PMID: 15987898 Free PMC article.

4

Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis.

Qiu X, Janson CA, Konstantinidis AK, Nwagwu S, Silverman C, Smith WW, Khandekar S, Lonsdale J, Abdel-Meguid SS. Qiu X, et al. J Biol Chem. 1999 Dec 17;274(51):36465-71. doi: 10.1074/jbc.274.51.36465. J Biol Chem. 1999. PMID: 10593943 Free article.

5

Expression, purification, and crystallization of the Escherichia coli selenomethionyl beta-ketoacyl-acyl carrier protein synthase III.

Khandekar SS, Konstantinidis AK, Silverman C, Janson CA, McNulty DE, Nwagwu S, Van Aller GS, Doyle ML, Kane JF, Qiu X, Lonsdale J. Khandekar SS, et al. Among authors: qiu x. Biochem Biophys Res Commun. 2000 Apr 2;270(1):100-7. doi: 10.1006/bbrc.2000.2380. Biochem Biophys Res Commun. 2000. PMID: 10733911

6

Refined structures of beta-ketoacyl-acyl carrier protein synthase III.

Qiu X, Janson CA, Smith WW, Head M, Lonsdale J, Konstantinidis AK. Qiu X, et al. J Mol Biol. 2001 Mar 16;307(1):341-56. doi: 10.1006/jmbi.2000.4457. J Mol Biol. 2001. PMID: 11243824

7

First X-ray cocrystal structure of a bacterial FabH condensing enzyme and a small molecule inhibitor achieved using rational design and homology modeling.

Daines RA, Pendrak I, Sham K, Van Aller GS, Konstantinidis AK, Lonsdale JT, Janson CA, Qiu X, Brandt M, Khandekar SS, Silverman C, Head MS. Daines RA, et al. Among authors: qiu x. J Med Chem. 2003 Jan 2;46(1):5-8. doi: 10.1021/jm025571b. J Med Chem. 2003. PMID: 12502353

8

Molecular basis for triclosan activity involves a flipping loop in the active site.

Qiu X, Janson CA, Court RI, Smyth MG, Payne DJ, Abdel-Meguid SS. Qiu X, et al. Protein Sci. 1999 Nov;8(11):2529-32. doi: 10.1110/ps.8.11.2529. Protein Sci. 1999. PMID: 10595560 Free PMC article.

9

1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI).

Heerding DA, Chan G, DeWolf WE, Fosberry AP, Janson CA, Jaworski DD, McManus E, Miller WH, Moore TD, Payne DJ, Qiu X, Rittenhouse SF, Slater-Radosti C, Smith W, Takata DT, Vaidya KS, Yuan CC, Huffman WF. Heerding DA, et al. Among authors: qiu x. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2061-5. doi: 10.1016/s0960-894x(01)00404-8. Bioorg Med Chem Lett. 2001. PMID: 11514139

10

Inhibitors of bacterial enoyl acyl carrier protein reductase (FabI): 2,9-disubstituted 1,2,3,4-tetrahydropyrido[3,4-b]indoles as potential antibacterial agents.

Seefeld MA, Miller WH, Newlander KA, Burgess WJ, Payne DJ, Rittenhouse SF, Moore TD, DeWolf WE Jr, Keller PM, Qiu X, Janson CA, Vaidya K, Fosberry AP, Smyth MG, Jaworski DD, Slater-Radosti C, Huffman WF. Seefeld MA, et al. Among authors: qiu x. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2241-4. doi: 10.1016/s0960-894x(01)00405-x. Bioorg Med Chem Lett. 2001. PMID: 11527706

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