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Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis.
Munugalavadla V, Sims EC, Borneo J, Chan RJ, Kapur R. Munugalavadla V, et al. Among authors: borneo j. Blood. 2007 Sep 1;110(5):1612-20. doi: 10.1182/blood-2006-10-053058. Epub 2007 May 4. Blood. 2007. PMID: 17483298 Free PMC article.
Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.
Ma P, Vemula S, Munugalavadla V, Chen J, Sims E, Borneo J, Kondo T, Ramdas B, Mali RS, Li S, Hashino E, Takemoto C, Kapur R. Ma P, et al. Among authors: borneo j. Mol Cell Biol. 2011 Oct;31(19):4052-62. doi: 10.1128/MCB.05750-11. Epub 2011 Jul 26. Mol Cell Biol. 2011. PMID: 21791602 Free PMC article.
Gut cytokines modulate olfaction through metabolic reprogramming of glia.
Cai XT, Li H, Borch Jensen M, Maksoud E, Borneo J, Liang Y, Quake SR, Luo L, Haghighi P, Jasper H. Cai XT, et al. Among authors: borneo j. Nature. 2021 Aug;596(7870):97-102. doi: 10.1038/s41586-021-03756-0. Epub 2021 Jul 21. Nature. 2021. PMID: 34290404 Free PMC article.
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