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Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.
Coghlan MP, Culbert AA, Cross DA, Corcoran SL, Yates JW, Pearce NJ, Rausch OL, Murphy GJ, Carter PS, Roxbee Cox L, Mills D, Brown MJ, Haigh D, Ward RW, Smith DG, Murray KJ, Reith AD, Holder JC. Coghlan MP, et al. Among authors: carter ps. Chem Biol. 2000 Oct;7(10):793-803. doi: 10.1016/s1074-5521(00)00025-9. Chem Biol. 2000. PMID: 11033082
The antimicrobial natural product chuangxinmycin and some synthetic analogues are potent and selective inhibitors of bacterial tryptophanyl tRNA synthetase.
Brown MJ, Carter PS, Fenwick AS, Fosberry AP, Hamprecht DW, Hibbs MJ, Jarvest RL, Mensah L, Milner PH, O'Hanlon PJ, Pope AJ, Richardson CM, West A, Witty DR. Brown MJ, et al. Among authors: carter ps. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3171-4. doi: 10.1016/s0960-894x(02)00604-2. Bioorg Med Chem Lett. 2002. PMID: 12372526
Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA Construct.
Chen YH, Pallant C, Sampson CJ, Boiti A, Johnson S, Brazauskas P, Hardwicke P, Marongiu M, Marinova VM, Carmo M, Sweeney NP, Richard A, Shillings A, Archibald P, Puschmann E, Mouzon B, Grose D, Mendez-Tavio M, Chen MX, Warr SRC, Senussi T, Carter PS, Baker S, Jung C, Brugman MH, Howe SJ, Vink CA. Chen YH, et al. Among authors: carter ps. Mol Ther Methods Clin Dev. 2020 Aug 14;19:47-57. doi: 10.1016/j.omtm.2020.08.011. eCollection 2020 Dec 11. Mol Ther Methods Clin Dev. 2020. PMID: 32995359 Free PMC article.
Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening.
Borthwick JA, Ancellin N, Bertrand SM, Bingham RP, Carter PS, Chung CW, Churcher I, Dodic N, Fournier C, Francis PL, Hobbs A, Jamieson C, Pickett SD, Smith SE, Somers DO, Spitzfaden C, Suckling CJ, Young RJ. Borthwick JA, et al. Among authors: carter ps. J Med Chem. 2016 Mar 24;59(6):2452-67. doi: 10.1021/acs.jmedchem.5b01607. Epub 2016 Mar 16. J Med Chem. 2016. PMID: 26938474 Free article.
31 results