Yankner BA - Search Results

1

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1.

Zhang Z, Nadeau P, Song W, Donoviel D, Yuan M, Bernstein A, Yankner BA. Zhang Z, et al. Among authors: yankner ba. Nat Cell Biol. 2000 Jul;2(7):463-5. doi: 10.1038/35017108. Nat Cell Biol. 2000. PMID: 10878814 No abstract available.

2

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations.

Song W, Nadeau P, Yuan M, Yang X, Shen J, Yankner BA. Song W, et al. Among authors: yankner ba. Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6959-63. doi: 10.1073/pnas.96.12.6959. Proc Natl Acad Sci U S A. 1999. PMID: 10359821 Free PMC article.

3

Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity.

Geula C, Wu CK, Saroff D, Lorenzo A, Yuan M, Yankner BA. Geula C, et al. Among authors: yankner ba. Nat Med. 1998 Jul;4(7):827-31. doi: 10.1038/nm0798-827. Nat Med. 1998. PMID: 9662375

4

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

Lorenzo A, Yuan M, Zhang Z, Paganetti PA, Sturchler-Pierrat C, Staufenbiel M, Mautino J, Vigo FS, Sommer B, Yankner BA. Lorenzo A, et al. Among authors: yankner ba. Nat Neurosci. 2000 May;3(5):460-4. doi: 10.1038/74833. Nat Neurosci. 2000. PMID: 10769385

5

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.

Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA. Zhang Z, et al. Among authors: yankner ba. Nature. 1998 Oct 15;395(6703):698-702. doi: 10.1038/27208. Nature. 1998. PMID: 9790190

6

Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium.

Isaacs AM, Senn DB, Yuan M, Shine JP, Yankner BA. Isaacs AM, et al. Among authors: yankner ba. J Biol Chem. 2006 Sep 22;281(38):27916-23. doi: 10.1074/jbc.M602061200. Epub 2006 Jul 26. J Biol Chem. 2006. PMID: 16870617 Free PMC article.

7

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease.

Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. Xu J, et al. Among authors: yankner ba. Nat Med. 2002 Jun;8(6):600-6. doi: 10.1038/nm0602-600. Nat Med. 2002. PMID: 12042811

8

beta-Trcp couples beta-catenin phosphorylation-degradation and regulates Xenopus axis formation.

Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X. Liu C, et al. Among authors: yankner ba. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6273-8. doi: 10.1073/pnas.96.11.6273. Proc Natl Acad Sci U S A. 1999. PMID: 10339577 Free PMC article.

9

Sorting Out Presenilins in Alzheimer's Disease.

Wolfe MS, Yankner BA. Wolfe MS, et al. Among authors: yankner ba. Cell. 2016 Jun 30;166(1):13-5. doi: 10.1016/j.cell.2016.06.034. Cell. 2016. PMID: 27368096 Free article.

10

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome.

Busciglio J, Pelsman A, Wong C, Pigino G, Yuan M, Mori H, Yankner BA. Busciglio J, et al. Among authors: yankner ba. Neuron. 2002 Feb 28;33(5):677-88. doi: 10.1016/s0896-6273(02)00604-9. Neuron. 2002. PMID: 11879646 Free article.

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