Chandy KG - Search Results

1

Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant.

Wulff H, Miller MJ, Hansel W, Grissmer S, Cahalan MD, Chandy KG. Wulff H, et al. Among authors: chandy kg. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8151-6. doi: 10.1073/pnas.97.14.8151. Proc Natl Acad Sci U S A. 2000. PMID: 10884437 Free PMC article.

2

Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel.

Ayabe T, Wulff H, Darmoul D, Cahalan MD, Chandy KG, Ouellette AJ. Ayabe T, et al. Among authors: chandy kg. J Biol Chem. 2002 Feb 1;277(5):3793-800. doi: 10.1074/jbc.M107507200. Epub 2001 Nov 27. J Biol Chem. 2002. PMID: 11724775 Free article.

3

Calmodulin mediates calcium-dependent activation of the intermediate conductance KCa channel, IKCa1.

Fanger CM, Ghanshani S, Logsdon NJ, Rauer H, Kalman K, Zhou J, Beckingham K, Chandy KG, Cahalan MD, Aiyar J. Fanger CM, et al. Among authors: chandy kg. J Biol Chem. 1999 Feb 26;274(9):5746-54. doi: 10.1074/jbc.274.9.5746. J Biol Chem. 1999. PMID: 10026195 Free article.

4

Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences.

Ghanshani S, Wulff H, Miller MJ, Rohm H, Neben A, Gutman GA, Cahalan MD, Chandy KG. Ghanshani S, et al. Among authors: chandy kg. J Biol Chem. 2000 Nov 24;275(47):37137-49. doi: 10.1074/jbc.M003941200. J Biol Chem. 2000. PMID: 10961988 Free article.

5

Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels.

Fanger CM, Rauer H, Neben AL, Miller MJ, Rauer H, Wulff H, Rosa JC, Ganellin CR, Chandy KG, Cahalan MD. Fanger CM, et al. Among authors: chandy kg. J Biol Chem. 2001 Apr 13;276(15):12249-56. doi: 10.1074/jbc.M011342200. Epub 2001 Jan 22. J Biol Chem. 2001. PMID: 11278890 Free article.

6

Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1.

Wulff H, Gutman GA, Cahalan MD, Chandy KG. Wulff H, et al. Among authors: chandy kg. J Biol Chem. 2001 Aug 24;276(34):32040-5. doi: 10.1074/jbc.M105231200. Epub 2001 Jun 25. J Biol Chem. 2001. PMID: 11425865 Free article.

7

Design and characterization of a highly selective peptide inhibitor of the small conductance calcium-activated K+ channel, SkCa2.

Shakkottai VG, Regaya I, Wulff H, Fajloun Z, Tomita H, Fathallah M, Cahalan MD, Gargus JJ, Sabatier JM, Chandy KG. Shakkottai VG, et al. Among authors: chandy kg. J Biol Chem. 2001 Nov 16;276(46):43145-51. doi: 10.1074/jbc.M106981200. Epub 2001 Aug 29. J Biol Chem. 2001. PMID: 11527975 Free article.

8

Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis.

Beeton C, Wulff H, Barbaria J, Clot-Faybesse O, Pennington M, Bernard D, Cahalan MD, Chandy KG, Béraud E. Beeton C, et al. Among authors: chandy kg. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13942-7. doi: 10.1073/pnas.241497298. Proc Natl Acad Sci U S A. 2001. PMID: 11717451 Free PMC article.

9

Expression and chromosomal localization of a lymphocyte K+ channel gene.

Grissmer S, Dethlefs B, Wasmuth JJ, Goldin AL, Gutman GA, Cahalan MD, Chandy KG. Grissmer S, et al. Among authors: chandy kg. Proc Natl Acad Sci U S A. 1990 Dec;87(23):9411-5. doi: 10.1073/pnas.87.23.9411. Proc Natl Acad Sci U S A. 1990. PMID: 2251283 Free PMC article.

10

A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes.

Beeton C, Wulff H, Singh S, Botsko S, Crossley G, Gutman GA, Cahalan MD, Pennington M, Chandy KG. Beeton C, et al. Among authors: chandy kg. J Biol Chem. 2003 Mar 14;278(11):9928-37. doi: 10.1074/jbc.M212868200. Epub 2003 Jan 2. J Biol Chem. 2003. PMID: 12511563 Free article.

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