Huang X - Search Results

1

Characterization of copper interactions with alzheimer amyloid beta peptides: identification of an attomolar-affinity copper binding site on amyloid beta1-42.

Atwood CS, Scarpa RC, Huang X, Moir RD, Jones WD, Fairlie DP, Tanzi RE, Bush AI. Atwood CS, et al. Among authors: huang x. J Neurochem. 2000 Sep;75(3):1219-33. doi: 10.1046/j.1471-4159.2000.0751219.x. J Neurochem. 2000. PMID: 10936205 Free article.

2

Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

Huang X, Atwood CS, Moir RD, Hartshorn MA, Vonsattel JP, Tanzi RE, Bush AI. Huang X, et al. J Biol Chem. 1997 Oct 17;272(42):26464-70. doi: 10.1074/jbc.272.42.26464. J Biol Chem. 1997. PMID: 9334223 Free article.

3

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

Atwood CS, Moir RD, Huang X, Scarpa RC, Bacarra NM, Romano DM, Hartshorn MA, Tanzi RE, Bush AI. Atwood CS, et al. Among authors: huang x. J Biol Chem. 1998 May 22;273(21):12817-26. doi: 10.1074/jbc.273.21.12817. J Biol Chem. 1998. PMID: 9582309 Free article.

4

Role of free radicals and metal ions in the pathogenesis of Alzheimer's disease.

Atwood CS, Huang X, Moir RD, Tanzi RE, Bush AI. Atwood CS, et al. Among authors: huang x. Met Ions Biol Syst. 1999;36:309-64. Met Ions Biol Syst. 1999. PMID: 10093929 Review. No abstract available.

5

Differential effects of apolipoprotein E isoforms on metal-induced aggregation of A beta using physiological concentrations.

Moir RD, Atwood CS, Romano DM, Laurans MH, Huang X, Bush AI, Smith JD, Tanzi RE. Moir RD, et al. Among authors: huang x. Biochemistry. 1999 Apr 6;38(14):4595-603. doi: 10.1021/bi982437d. Biochemistry. 1999. PMID: 10194381

6

The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction.

Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, Cuajungco MP, Gray DN, Lim J, Moir RD, Tanzi RE, Bush AI. Huang X, et al. Biochemistry. 1999 Jun 15;38(24):7609-16. doi: 10.1021/bi990438f. Biochemistry. 1999. PMID: 10386999

7

Mounting evidence for the involvement of zinc and copper in Alzheimer's disease.

Moir RD, Atwood CS, Huang X, Tanzi RE, Bush AI. Moir RD, et al. Among authors: huang x. Eur J Clin Invest. 1999 Jul;29(7):569-70. doi: 10.1046/j.1365-2362.1999.00472.x. Eur J Clin Invest. 1999. PMID: 10411660 Review. No abstract available.

8

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion.

Cherny RA, Legg JT, McLean CA, Fairlie DP, Huang X, Atwood CS, Beyreuther K, Tanzi RE, Masters CL, Bush AI. Cherny RA, et al. Among authors: huang x. J Biol Chem. 1999 Aug 13;274(33):23223-8. doi: 10.1074/jbc.274.33.23223. J Biol Chem. 1999. PMID: 10438495 Free article.

9

The possible origin of free radicals from amyloid beta peptides in Alzheimer's disease.

Bus AI, Huang X, Fairlie DP. Bus AI, et al. Among authors: huang x. Neurobiol Aging. 1999 May-Jun;20(3):335-7; discussion 339-42. doi: 10.1016/s0197-4580(99)00058-5. Neurobiol Aging. 1999. PMID: 10588582 Review. No abstract available.

10

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR, Stokes KC, Leopold M, Multhaup G, Goldstein LE, Scarpa RC, Saunders AJ, Lim J, Moir RD, Glabe C, Bowden EF, Masters CL, Fairlie DP, Tanzi RE, Bush AI. Huang X, et al. J Biol Chem. 1999 Dec 24;274(52):37111-6. doi: 10.1074/jbc.274.52.37111. J Biol Chem. 1999. PMID: 10601271 Free article.

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