LeMotte PK - Search Results

1

A crystallizable form of RIIbeta regulatory domain obtained by limited proteolysis.

Danley DE, Haggan ME, Cunningham D, Fennell KF, Pauly TA, LeMotte PK. Danley DE, et al. Among authors: lemotte pk. Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):1038-41. doi: 10.1107/s0907444900007150. Acta Crystallogr D Biol Crystallogr. 2000. PMID: 10944347

2

Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.

Rath VL, Ammirati M, LeMotte PK, Fennell KF, Mansour MN, Danley DE, Hynes TR, Schulte GK, Wasilko DJ, Pandit J. Rath VL, et al. Among authors: lemotte pk. Mol Cell. 2000 Jul;6(1):139-48. Mol Cell. 2000. PMID: 10949035 Free article.

3

The 2.0 A crystal structure of the ERalpha ligand-binding domain complexed with lasofoxifene.

Vajdos FF, Hoth LR, Geoghegan KF, Simons SP, LeMotte PK, Danley DE, Ammirati MJ, Pandit J. Vajdos FF, et al. Among authors: lemotte pk. Protein Sci. 2007 May;16(5):897-905. doi: 10.1110/ps.062729207. Protein Sci. 2007. PMID: 17456742 Free PMC article.

4

Structural basis for the catalytic mechanism of human phosphodiesterase 9.

Liu S, Mansour MN, Dillman KS, Perez JR, Danley DE, Aeed PA, Simons SP, Lemotte PK, Menniti FS. Liu S, et al. Among authors: lemotte pk. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13309-14. doi: 10.1073/pnas.0708850105. Epub 2008 Aug 29. Proc Natl Acad Sci U S A. 2008. PMID: 18757755 Free PMC article.

5

Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TR beta subtype-selective thyromimetics.

Dow RL, Schneider SR, Paight ES, Hank RF, Chiang P, Cornelius P, Lee E, Newsome WP, Swick AG, Spitzer J, Hargrove DM, Patterson TA, Pandit J, Chrunyk BA, LeMotte PK, Danley DE, Rosner MH, Ammirati MJ, Simons SP, Schulte GK, Tate BF, DaSilva-Jardine P. Dow RL, et al. Among authors: lemotte pk. Bioorg Med Chem Lett. 2003 Feb 10;13(3):379-82. doi: 10.1016/s0960-894x(02)00947-2. Bioorg Med Chem Lett. 2003. PMID: 12565933

6

Theoretical and experimental design of atypical kinase inhibitors: application to p38 MAP kinase.

McClure KF, Abramov YA, Laird ER, Barberia JT, Cai W, Carty TJ, Cortina SR, Danley DE, Dipesa AJ, Donahue KM, Dombroski MA, Elliott NC, Gabel CA, Han S, Hynes TR, Lemotte PK, Mansour MN, Marr ES, Letavic MA, Pandit J, Ripin DB, Sweeney FJ, Tan D, Tao Y. McClure KF, et al. Among authors: lemotte pk. J Med Chem. 2005 Sep 8;48(18):5728-37. doi: 10.1021/jm050346q. J Med Chem. 2005. PMID: 16134941

7

Spontaneous alpha-N-6-phosphogluconoylation of a "His tag" in Escherichia coli: the cause of extra mass of 258 or 178 Da in fusion proteins.

Geoghegan KF, Dixon HB, Rosner PJ, Hoth LR, Lanzetti AJ, Borzilleri KA, Marr ES, Pezzullo LH, Martin LB, LeMotte PK, McColl AS, Kamath AV, Stroh JG. Geoghegan KF, et al. Among authors: lemotte pk. Anal Biochem. 1999 Feb 1;267(1):169-84. doi: 10.1006/abio.1998.2990. Anal Biochem. 1999. PMID: 9918669

8

Structures of cellular retinoic acid binding proteins I and II in complex with synthetic retinoids.

Chaudhuri BN, Kleywegt GJ, Broutin-L'Hermite I, Bergfors T, Senn H, Le Motte P, Partouche O, Jones TA. Chaudhuri BN, et al. Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1850-7. doi: 10.1107/s0907444999011026. Acta Crystallogr D Biol Crystallogr. 1999. PMID: 10531482

9

Phosphorylation of serine residues in histidine-tag sequences attached to recombinant protein kinases: a cause of heterogeneity in mass and complications in function.

Du P, Loulakis P, Luo C, Mistry A, Simons SP, LeMotte PK, Rajamohan F, Rafidi K, Coleman KG, Geoghegan KF, Xie Z. Du P, et al. Among authors: lemotte pk. Protein Expr Purif. 2005 Dec;44(2):121-9. doi: 10.1016/j.pep.2005.04.018. Protein Expr Purif. 2005. PMID: 15946859

10

Purification of the large ribosomal subunit via its association with the small subunit.

Simons SP, McLellan TJ, Aeed PA, Zaniewski RP, Desbonnet CR, Wondrack LM, Marr ES, Subashi TA, Dougherty TJ, Xu Z, Wang IK, LeMotte PK, Maguire BA. Simons SP, et al. Among authors: lemotte pk. Anal Biochem. 2009 Dec 1;395(1):77-85. doi: 10.1016/j.ab.2009.07.042. Epub 2009 Jul 30. Anal Biochem. 2009. PMID: 19646947

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