Hirai H - Search Results

1

Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis.

Imai Y, Kurokawa M, Izutsu K, Hangaishi A, Takeuchi K, Maki K, Ogawa S, Chiba S, Mitani K, Hirai H. Imai Y, et al. Among authors: hirai h. Blood. 2000 Nov 1;96(9):3154-60. Blood. 2000. PMID: 11049997 Free article.

2

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

Tanaka T, Tanaka K, Ogawa S, Kurokawa M, Mitani K, Nishida J, Shibata Y, Yazaki Y, Hirai H. Tanaka T, et al. Among authors: hirai h. EMBO J. 1995 Jan 16;14(2):341-50. doi: 10.1002/j.1460-2075.1995.tb07008.x. EMBO J. 1995. PMID: 7530657 Free PMC article.

3

Increased expression of AML1 during retinoic-acid-induced differentiation of U937 cells.

Tanaka K, Tanaka T, Ogawa S, Kurokawa M, Mitani K, Yazaki Y, Hirai H. Tanaka K, et al. Among authors: hirai h. Biochem Biophys Res Commun. 1995 Jun 26;211(3):1023-30. doi: 10.1006/bbrc.1995.1913. Biochem Biophys Res Commun. 1995. PMID: 7598688

4

The AML1/Evi-1 fusion protein in the t(3;21) translocation exhibits transforming activity on Rat1 fibroblasts with dependence on the Evi-1 sequence.

Kurokawa M, Ogawa S, Tanaka T, Mitani K, Yazaki Y, Witte ON, Hirai H. Kurokawa M, et al. Among authors: hirai h. Oncogene. 1995 Sep 7;11(5):833-40. Oncogene. 1995. PMID: 7675444

5

Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation.

Mitani K, Kanda Y, Ogawa S, Tanaka T, Inazawa J, Yazaki Y, Hirai H. Mitani K, et al. Among authors: hirai h. Blood. 1995 Apr 15;85(8):2017-24. Blood. 1995. PMID: 7718874 Free article.

6

Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.

Tanaka T, Mitani K, Kurokawa M, Ogawa S, Tanaka K, Nishida J, Yazaki Y, Shibata Y, Hirai H. Tanaka T, et al. Among authors: hirai h. Mol Cell Biol. 1995 May;15(5):2383-92. doi: 10.1128/MCB.15.5.2383. Mol Cell Biol. 1995. PMID: 7739522 Free PMC article.

7

Mutations of the p53 gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia.

Sugimoto K, Hirano N, Toyoshima H, Chiba S, Mano H, Takaku F, Yazaki Y, Hirai H. Sugimoto K, et al. Among authors: hirai h. Blood. 1993 Jun 1;81(11):3022-6. Blood. 1993. PMID: 8499637 Free article.

8

Overexpression of the AML1 proto-oncoprotein in NIH3T3 cells leads to neoplastic transformation depending on the DNA-binding and transactivational potencies.

Kurokawa M, Tanaka T, Tanaka K, Ogawa S, Mitani K, Yazaki Y, Hirai H. Kurokawa M, et al. Among authors: hirai h. Oncogene. 1996 Feb 15;12(4):883-92. Oncogene. 1996. PMID: 8632911

9

Inactivation of multiple tumor-suppressor genes involved in negative regulation of the cell cycle, MTS1/p16INK4A/CDKN2, MTS2/p15INK4B, p53, and Rb genes in primary lymphoid malignancies.

Hangaishi A, Ogawa S, Imamura N, Miyawaki S, Miura Y, Uike N, Shimazaki C, Emi N, Takeyama K, Hirosawa S, Kamada N, Kobayashi Y, Takemoto Y, Kitani T, Toyama K, Ohtake S, Yazaki Y, Ueda R, Hirai H. Hangaishi A, et al. Among authors: hirai h. Blood. 1996 Jun 15;87(12):4949-58. Blood. 1996. PMID: 8652807 Free article.

10

A conserved cysteine residue in the runt homology domain of AML1 is required for the DNA binding ability and the transforming activity on fibroblasts.

Kurokawa M, Tanaka T, Tanaka K, Hirano N, Ogawa S, Mitani K, Yazaki Y, Hirai H. Kurokawa M, et al. Among authors: hirai h. J Biol Chem. 1996 Jul 12;271(28):16870-6. doi: 10.1074/jbc.271.28.16870. J Biol Chem. 1996. PMID: 8663420 Free article.

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