Kahn CR - Search Results

1

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha.

Fruman DA, Mauvais-Jarvis F, Pollard DA, Yballe CM, Brazil D, Bronson RT, Kahn CR, Cantley LC. Fruman DA, et al. Among authors: kahn cr. Nat Genet. 2000 Nov;26(3):379-82. doi: 10.1038/81715. Nat Genet. 2000. PMID: 11062485

2

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

Sun XJ, Rothenberg P, Kahn CR, Backer JM, Araki E, Wilden PA, Cahill DA, Goldstein BJ, White MF. Sun XJ, et al. Among authors: kahn cr. Nature. 1991 Jul 4;352(6330):73-7. doi: 10.1038/352073a0. Nature. 1991. PMID: 1648180

3

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

Araki E, Lipes MA, Patti ME, Brüning JC, Haag B 3rd, Johnson RS, Kahn CR. Araki E, et al. Among authors: kahn cr. Nature. 1994 Nov 10;372(6502):186-90. doi: 10.1038/372186a0. Nature. 1994. PMID: 7526222

4

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle.

Kim JK, Michael MD, Previs SF, Peroni OD, Mauvais-Jarvis F, Neschen S, Kahn BB, Kahn CR, Shulman GI. Kim JK, et al. Among authors: kahn bb, kahn cr. J Clin Invest. 2000 Jun;105(12):1791-7. doi: 10.1172/JCI8305. J Clin Invest. 2000. PMID: 10862794 Free PMC article.

5

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

Zisman A, Peroni OD, Abel ED, Michael MD, Mauvais-Jarvis F, Lowell BB, Wojtaszewski JF, Hirshman MF, Virkamaki A, Goodyear LJ, Kahn CR, Kahn BB. Zisman A, et al. Among authors: kahn bb, kahn cr. Nat Med. 2000 Aug;6(8):924-8. doi: 10.1038/78693. Nat Med. 2000. PMID: 10932232

6

Positive and negative regulation of phosphoinositide 3-kinase-dependent signaling pathways by three different gene products of the p85alpha regulatory subunit.

Ueki K, Algenstaedt P, Mauvais-Jarvis F, Kahn CR. Ueki K, et al. Among authors: kahn cr. Mol Cell Biol. 2000 Nov;20(21):8035-46. doi: 10.1128/MCB.20.21.8035-8046.2000. Mol Cell Biol. 2000. PMID: 11027274 Free PMC article.

7

A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.

Mauvais-Jarvis F, Virkamaki A, Michael MD, Winnay JN, Zisman A, Kulkarni RN, Kahn CR. Mauvais-Jarvis F, et al. Among authors: kahn cr. Diabetes. 2000 Dec;49(12):2126-34. doi: 10.2337/diabetes.49.12.2126. Diabetes. 2000. PMID: 11118016

8

Understanding the pathogenesis and treatment of insulin resistance and type 2 diabetes mellitus: what can we learn from transgenic and knockout mice?

Mauvais-Jarvis F, Kahn CR. Mauvais-Jarvis F, et al. Among authors: kahn cr. Diabetes Metab. 2000 Dec;26(6):433-48. Diabetes Metab. 2000. PMID: 11173714 Review.

9

Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase.

Ueki K, Yballe CM, Brachmann SM, Vicent D, Watt JM, Kahn CR, Cantley LC. Ueki K, et al. Among authors: kahn cr. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):419-24. doi: 10.1073/pnas.012581799. Epub 2001 Dec 18. Proc Natl Acad Sci U S A. 2002. PMID: 11752399 Free PMC article.

10

Reduced expression of the murine p85alpha subunit of phosphoinositide 3-kinase improves insulin signaling and ameliorates diabetes.

Mauvais-Jarvis F, Ueki K, Fruman DA, Hirshman MF, Sakamoto K, Goodyear LJ, Iannacone M, Accili D, Cantley LC, Kahn CR. Mauvais-Jarvis F, et al. Among authors: kahn cr. J Clin Invest. 2002 Jan;109(1):141-9. doi: 10.1172/JCI13305. J Clin Invest. 2002. PMID: 11781359 Free PMC article.

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