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Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores: further evidence that some cases of platelet 'primary secretion defect' are heterozygous for a defect of P2CYC receptors.
Cattaneo M, Lecchi A, Lombardi R, Gachet C, Zighetti ML. Cattaneo M, et al. Among authors: gachet c. Arterioscler Thromb Vasc Biol. 2000 Nov;20(11):E101-6. doi: 10.1161/01.atv.20.11.e101. Arterioscler Thromb Vasc Biol. 2000. PMID: 11073862
Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates and thromboxane A2 production.
Cattaneo M, Lombardi R, Zighetti ML, Gachet C, Ohlmann P, Cazenave JP, Mannucci PM. Cattaneo M, et al. Among authors: gachet c. Thromb Haemost. 1997 May;77(5):986-90. Thromb Haemost. 1997. PMID: 9184415
ADP receptors and clinical bleeding disorders.
Cattaneo M, Gachet C. Cattaneo M, et al. Among authors: gachet c. Arterioscler Thromb Vasc Biol. 1999 Oct;19(10):2281-5. doi: 10.1161/01.atv.19.10.2281. Arterioscler Thromb Vasc Biol. 1999. PMID: 10521355 Review.
The P2 receptors in platelet function.
Hechler B, Cattaneo M, Gachet C. Hechler B, et al. Among authors: gachet c. Semin Thromb Hemost. 2005 Apr;31(2):150-61. doi: 10.1055/s-2005-869520. Semin Thromb Hemost. 2005. PMID: 15852218 Review.
Severe bleeding and absent ADP-induced platelet aggregation associated with inherited combined CalDAG-GEFI and P2Y12 deficiencies.
Lunghi B, Lecchi A, Santacroce R, Scavone M, Paniccia R, Artoni A, Gachet C, Castaman G, Margaglione M, Bernardi F, Cattaneo M. Lunghi B, et al. Among authors: gachet c. Haematologica. 2020 Jul;105(7):e361-e364. doi: 10.3324/haematol.2019.232850. Epub 2019 Oct 24. Haematologica. 2020. PMID: 31649128 Free PMC article. No abstract available.
The platelet ADP receptors.
Cattaneo M, Gachet C. Cattaneo M, et al. Among authors: gachet c. Haematologica. 2001 Apr;86(4):346-8. Haematologica. 2001. PMID: 11325637 Review. No abstract available.
Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt].
Hechler B, Magnenat S, Zighetti ML, Kassack MU, Ullmann H, Cazenave JP, Evans R, Cattaneo M, Gachet C. Hechler B, et al. Among authors: gachet c. J Pharmacol Exp Ther. 2005 Jul;314(1):232-43. doi: 10.1124/jpet.105.084673. Epub 2005 Mar 25. J Pharmacol Exp Ther. 2005. PMID: 15792995
337 results