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Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow.
Shiozawa Y, Pedersen EA, Havens AM, Jung Y, Mishra A, Joseph J, Kim JK, Patel LR, Ying C, Ziegler AM, Pienta MJ, Song J, Wang J, Loberg RD, Krebsbach PH, Pienta KJ, Taichman RS. Shiozawa Y, et al. Among authors: taichman rs. J Clin Invest. 2011 Apr;121(4):1298-312. doi: 10.1172/JCI43414. Epub 2011 Mar 23. J Clin Invest. 2011. PMID: 21436587 Free PMC article.
Hematopoietic stem cells regulate mesenchymal stromal cell induction into osteoblasts thereby participating in the formation of the stem cell niche.
Jung Y, Song J, Shiozawa Y, Wang J, Wang Z, Williams B, Havens A, Schneider A, Ge C, Franceschi RT, McCauley LK, Krebsbach PH, Taichman RS. Jung Y, et al. Among authors: taichman rs. Stem Cells. 2008 Aug;26(8):2042-51. doi: 10.1634/stemcells.2008-0149. Epub 2008 May 22. Stem Cells. 2008. PMID: 18499897 Free PMC article.
Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis.
Wang J, Wang J, Sun Y, Song W, Nor JE, Wang CY, Taichman RS. Wang J, et al. Among authors: taichman rs. Cell Signal. 2005 Dec;17(12):1578-92. doi: 10.1016/j.cellsig.2005.03.022. Cell Signal. 2005. Retraction in: Cell Signal. 2021 Apr;80:109909. doi: 10.1016/j.cellsig.2020.109909 PMID: 16005185 Retracted.
Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo.
Sun YX, Schneider A, Jung Y, Wang J, Dai J, Wang J, Cook K, Osman NI, Koh-Paige AJ, Shim H, Pienta KJ, Keller ET, McCauley LK, Taichman RS. Sun YX, et al. Among authors: taichman rs. J Bone Miner Res. 2005 Feb;20(2):318-29. doi: 10.1359/JBMR.041109. Epub 2004 Nov 16. J Bone Miner Res. 2005. PMID: 15647826 Free article.
185 results