Rottapel R - Search Results

1

A point mutation in CD28 distinguishes proliferative signals from survival signals.

Okkenhaug K, Wu L, Garza KM, La Rose J, Khoo W, Odermatt B, Mak TW, Ohashi PS, Rottapel R. Okkenhaug K, et al. Among authors: rottapel r. Nat Immunol. 2001 Apr;2(4):325-32. doi: 10.1038/86327. Nat Immunol. 2001. PMID: 11276203

2

CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway.

Wu LX, La Rose J, Chen L, Neale C, Mak T, Okkenhaug K, Wange R, Rottapel R. Wu LX, et al. Among authors: rottapel r. J Immunol. 2005 Jan 1;174(1):180-94. doi: 10.4049/jimmunol.174.1.180. J Immunol. 2005. PMID: 15611240

3

Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction.

Okkenhaug K, Rottapel R. Okkenhaug K, et al. Among authors: rottapel r. J Biol Chem. 1998 Aug 14;273(33):21194-202. doi: 10.1074/jbc.273.33.21194. J Biol Chem. 1998. PMID: 9694876 Free article.

4

The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28.

Marengère LE, Okkenhaug K, Clavreul A, Couez D, Gibson S, Mills GB, Mak TW, Rottapel R. Marengère LE, et al. Among authors: rottapel r. J Immunol. 1997 Oct 1;159(7):3220-9. J Immunol. 1997. PMID: 9317120

5

A positive regulatory role for suppressor of cytokine signaling 1 in IFN-gamma-induced MHC class II expression in fibroblasts.

Ilangumaran S, Finan D, La Rose J, Raine J, Silverstein A, De Sepulveda P, Rottapel R. Ilangumaran S, et al. Among authors: rottapel r. J Immunol. 2002 Nov 1;169(9):5010-20. doi: 10.4049/jimmunol.169.9.5010. J Immunol. 2002. PMID: 12391216

6

Suppressor of cytokine signaling 1 regulates IL-15 receptor signaling in CD8+CD44high memory T lymphocytes.

Ilangumaran S, Ramanathan S, La Rose J, Poussier P, Rottapel R. Ilangumaran S, et al. Among authors: rottapel r. J Immunol. 2003 Sep 1;171(5):2435-45. doi: 10.4049/jimmunol.171.5.2435. J Immunol. 2003. PMID: 12928391

7

CD28-dependent activation of protein kinase B/Akt blocks Fas-mediated apoptosis by preventing death-inducing signaling complex assembly.

Jones RG, Elford AR, Parsons MJ, Wu L, Krawczyk CM, Yeh WC, Hakem R, Rottapel R, Woodgett JR, Ohashi PS. Jones RG, et al. Among authors: rottapel r. J Exp Med. 2002 Aug 5;196(3):335-48. doi: 10.1084/jem.20020307. J Exp Med. 2002. PMID: 12163562 Free PMC article.

8

The tumor suppressor activity of SOCS-1.

Rottapel R, Ilangumaran S, Neale C, La Rose J, Ho JM, Nguyen MH, Barber D, Dubreuil P, de Sepulveda P. Rottapel R, et al. Oncogene. 2002 Jun 27;21(28):4351-62. doi: 10.1038/sj.onc.1205537. Oncogene. 2002. PMID: 12080466

9

Autoinhibition of the kit receptor tyrosine kinase by the cytosolic juxtamembrane region.

Chan PM, Ilangumaran S, La Rose J, Chakrabartty A, Rottapel R. Chan PM, et al. Among authors: rottapel r. Mol Cell Biol. 2003 May;23(9):3067-78. doi: 10.1128/MCB.23.9.3067-3078.2003. Mol Cell Biol. 2003. PMID: 12697809 Free PMC article.

10

The 3BP2 adapter protein is required for optimal B-cell activation and thymus-independent type 2 humoral response.

Chen G, Dimitriou ID, La Rose J, Ilangumaran S, Yeh WC, Doody G, Turner M, Gommerman J, Rottapel R. Chen G, et al. Among authors: rottapel r. Mol Cell Biol. 2007 Apr;27(8):3109-22. doi: 10.1128/MCB.01014-06. Epub 2007 Feb 5. Mol Cell Biol. 2007. PMID: 17283041 Free PMC article.

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