Jamil H - Search Results

1

A novel series of highly potent benzimidazole-based microsomal triglyceride transfer protein inhibitors.

Robl JA, Sulsky R, Sun CQ, Simpkins LM, Wang T, Dickson JK Jr, Chen Y, Magnin DR, Taunk P, Slusarchyk WA, Biller SA, Lan SJ, Connolly F, Kunselman LK, Sabrah T, Jamil H, Gordon D, Harrity TW, Wetterau JR. Robl JA, et al. Among authors: jamil h. J Med Chem. 2001 Mar 15;44(6):851-6. doi: 10.1021/jm000494a. J Med Chem. 2001. PMID: 11300866

2

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.

Li JJ, Wang H, Tino JA, Robl JA, Herpin TF, Lawrence RM, Biller S, Jamil H, Ponticiello R, Chen L, Chu CH, Flynn N, Cheng D, Zhao R, Chen B, Schnur D, Obermeier MT, Sasseville V, Padmanabha R, Pike K, Harrity T. Li JJ, et al. Among authors: jamil h. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3208-11. doi: 10.1016/j.bmcl.2007.03.017. Epub 2007 Mar 12. Bioorg Med Chem Lett. 2007. PMID: 17383874

3

Microsomal triglyceride transfer protein. Specificity of lipid binding and transport.

Jamil H, Dickson JK Jr, Chu CH, Lago MW, Rinehart JK, Biller SA, Gregg RE, Wetterau JR. Jamil H, et al. J Biol Chem. 1995 Mar 24;270(12):6549-54. doi: 10.1074/jbc.270.12.6549. J Biol Chem. 1995. PMID: 7896791 Free article.

4

An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells.

Jamil H, Gordon DA, Eustice DC, Brooks CM, Dickson JK Jr, Chen Y, Ricci B, Chu CH, Harrity TW, Ciosek CP Jr, Biller SA, Gregg RE, Wetterau JR. Jamil H, et al. Proc Natl Acad Sci U S A. 1996 Oct 15;93(21):11991-5. doi: 10.1073/pnas.93.21.11991. Proc Natl Acad Sci U S A. 1996. PMID: 8876250 Free PMC article.

5

Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step.

Gordon DA, Jamil H, Gregg RE, Olofsson SO, Borén J. Gordon DA, et al. Among authors: jamil h. J Biol Chem. 1996 Dec 20;271(51):33047-53. doi: 10.1074/jbc.271.51.33047. J Biol Chem. 1996. PMID: 8955151 Free article.

6

Microsomal triglyceride transfer protein.

Wetterau JR, Lin MC, Jamil H. Wetterau JR, et al. Among authors: jamil h. Biochim Biophys Acta. 1997 Apr 1;1345(2):136-50. doi: 10.1016/s0005-2760(96)00168-3. Biochim Biophys Acta. 1997. PMID: 9106493 Review. No abstract available.

7

Evidence that microsomal triglyceride transfer protein is limiting in the production of apolipoprotein B-containing lipoproteins in hepatic cells.

Jamil H, Chu CH, Dickson JK Jr, Chen Y, Yan M, Biller SA, Gregg RE, Wetterau JR, Gordon DA. Jamil H, et al. J Lipid Res. 1998 Jul;39(7):1448-54. J Lipid Res. 1998. PMID: 9684748 Free article.

8

An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits.

Wetterau JR, Gregg RE, Harrity TW, Arbeeny C, Cap M, Connolly F, Chu CH, George RJ, Gordon DA, Jamil H, Jolibois KG, Kunselman LK, Lan SJ, Maccagnan TJ, Ricci B, Yan M, Young D, Chen Y, Fryszman OM, Logan JV, Musial CL, Poss MA, Robl JA, Simpkins LM, Slusarchyk WA, Sulsky R, Taunk P, Magnin DR, Tino JA, Lawrence RM, Dickson JK Jr, Biller SA. Wetterau JR, et al. Among authors: jamil h. Science. 1998 Oct 23;282(5389):751-4. doi: 10.1126/science.282.5389.751. Science. 1998. PMID: 9784135

9

Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly.

Gordon DA, Jamil H. Gordon DA, et al. Among authors: jamil h. Biochim Biophys Acta. 2000 Jun 26;1486(1):72-83. doi: 10.1016/s1388-1981(00)00049-4. Biochim Biophys Acta. 2000. PMID: 10856714 Review.

10

Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability.

Gordon DA, Jamil H, Sharp D, Mullaney D, Yao Z, Gregg RE, Wetterau J. Gordon DA, et al. Among authors: jamil h. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7628-32. doi: 10.1073/pnas.91.16.7628. Proc Natl Acad Sci U S A. 1994. PMID: 8052632 Free PMC article.

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