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Both total and phosphorylated tau are increased in Alzheimer's disease.
Sjögren M, Davidsson P, Tullberg M, Minthon L, Wallin A, Wikkelso C, Granérus AK, Vanderstichele H, Vanmechelen E, Blennow K. Sjögren M, et al. Among authors: vanderstichele h. J Neurol Neurosurg Psychiatry. 2001 May;70(5):624-30. doi: 10.1136/jnnp.70.5.624. J Neurol Neurosurg Psychiatry. 2001. PMID: 11309456 Free PMC article.
The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process.
Sjögren M, Davidsson P, Gottfries J, Vanderstichele H, Edman A, Vanmechelen E, Wallin A, Blennow K. Sjögren M, et al. Among authors: vanderstichele h. Dement Geriatr Cogn Disord. 2001 Jul-Aug;12(4):257-64. doi: 10.1159/000051268. Dement Geriatr Cogn Disord. 2001. PMID: 11351137
The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease.
Hoglund K, Thelen KM, Syversen S, Sjogren M, von Bergmann K, Wallin A, Vanmechelen E, Vanderstichele H, Lutjohann D, Blennow K. Hoglund K, et al. Among authors: vanderstichele h. Dement Geriatr Cogn Disord. 2005;19(5-6):256-65. doi: 10.1159/000084550. Epub 2005 Mar 21. Dement Geriatr Cogn Disord. 2005. PMID: 15785028
159 results