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A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.
Southwell AL, Skotte NH, Villanueva EB, Østergaard ME, Gu X, Kordasiewicz HB, Kay C, Cheung D, Xie Y, Waltl S, Dal Cengio L, Findlay-Black H, Doty CN, Petoukhov E, Iworima D, Slama R, Ooi J, Pouladi MA, Yang XW, Swayze EE, Seth PP, Hayden MR. Southwell AL, et al. Among authors: cheung d. Hum Mol Genet. 2017 Mar 15;26(6):1115-1132. doi: 10.1093/hmg/ddx021. Hum Mol Genet. 2017. PMID: 28104789
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes.
Southwell AL, Smith-Dijak A, Kay C, Sepers M, Villanueva EB, Parsons MP, Xie Y, Anderson L, Felczak B, Waltl S, Ko S, Cheung D, Dal Cengio L, Slama R, Petoukhov E, Raymond LA, Hayden MR. Southwell AL, et al. Among authors: cheung d. Hum Mol Genet. 2016 Sep 1;25(17):3654-3675. doi: 10.1093/hmg/ddw212. Epub 2016 Jul 4. Hum Mol Genet. 2016. PMID: 27378694 Free PMC article.
Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease.
Caron NS, Banos R, Yanick C, Aly AE, Byrne LM, Smith ED, Xie Y, Smith SEP, Potluri N, Findlay Black H, Casal L, Ko S, Cheung D, Kim H, Seong IS, Wild EJ, Song JJ, Hayden MR, Southwell AL. Caron NS, et al. Among authors: cheung d. J Neurosci. 2021 Jan 27;41(4):780-796. doi: 10.1523/JNEUROSCI.1865-20.2020. Epub 2020 Dec 11. J Neurosci. 2021. PMID: 33310753 Free PMC article.
Morphologic and Molecular Characteristics of Mixed Epithelial Ovarian Cancers.
Mackenzie R, Talhouk A, Eshragh S, Lau S, Cheung D, Chow C, Le N, Cook LS, Wilkinson N, McDermott J, Singh N, Kommoss F, Pfisterer J, Huntsman DG, Köbel M, Kommoss S, Gilks CB, Anglesio MS. Mackenzie R, et al. Among authors: cheung d. Am J Surg Pathol. 2015 Nov;39(11):1548-57. doi: 10.1097/PAS.0000000000000476. Am J Surg Pathol. 2015. PMID: 26099008 Free PMC article.
Bridging the Two Worlds: Worldwide Reflections on the 2024 Hong Kong SAR/PolyU Conference.
Yung JW, Bromley A, Chae Y, Cheung DST, Conboy L, Graca S, Levett K, Lumiere K, Schnyer R, Sparrow K, Tseng L, Yoo J, Zhang YQ, Citkovitz C. Yung JW, et al. Among authors: cheung dst. J Integr Complement Med. 2024 Nov 11. doi: 10.1089/jicm.2024.0819. Online ahead of print. J Integr Complement Med. 2024. PMID: 39527006 No abstract available.
Safety principles for medical summarization using generative AI.
Obika D, Kelly C, Ding N, Farrance C, Krause J, Mittal P, Cheung D, Cole-Lewis H, Elish M, Karthikesalingam A, Webster D, Patel B, Howell M. Obika D, et al. Among authors: cheung d. Nat Med. 2024 Oct 22. doi: 10.1038/s41591-024-03313-y. Online ahead of print. Nat Med. 2024. PMID: 39438665 No abstract available.
909 results