Mutational analysis of the relative orientation of transmembrane helices I and VII in G protein-coupled receptors.
Liu J, Schöneberg T, van Rhee M, Wess J.
Liu J, et al. Among authors: wess j.
J Biol Chem. 1995 Aug 18;270(33):19532-9. doi: 10.1074/jbc.270.33.19532.
J Biol Chem. 1995.
PMID: 7642637
Free article.
We demonstrated previously that hybrid m2/m5 muscarinic acetylcholine receptors which contain m5 sequence in TM I and m2 sequence in TM VII were unable to bind significant amounts of muscarinic radioligands (Pittel, Z., and Wess, J. (1994) Mol. Pharmacol. 45, 61-64) …
We demonstrated previously that hybrid m2/m5 muscarinic acetylcholine receptors which contain m5 sequence in TM I and m2 sequence in TM VII …