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Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2.
Hilgenfeld E, Padilla-Nash H, McNeil N, Knutsen T, Montagna C, Tchinda J, Horst J, Ludwig WD, Serve H, Büchner T, Berdel WE, Schröck E, Ried T. Hilgenfeld E, et al. Among authors: knutsen t. Br J Haematol. 2001 May;113(2):305-17. doi: 10.1046/j.1365-2141.2001.02723.x. Br J Haematol. 2001. PMID: 11380393 Free article.
Cytogenetic, spectral karyotyping, fluorescence in situ hybridization, and comparative genomic hybridization characterization of two new secondary leukemia cell lines with 5q deletions, and MYC and MLL amplification.
Knutsen T, Pack S, Petropavlovskaja M, Padilla-Nash H, Knight C, Mickley LA, Ried T, Elwood PC, Roberts SJ. Knutsen T, et al. Genes Chromosomes Cancer. 2003 Jul;37(3):270-81. doi: 10.1002/gcc.10200. Genes Chromosomes Cancer. 2003. PMID: 12759925
Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances.
Padilla-Nash HM, Hathcock K, McNeil NE, Mack D, Hoeppner D, Ravin R, Knutsen T, Yonescu R, Wangsa D, Dorritie K, Barenboim L, Hu Y, Ried T. Padilla-Nash HM, et al. Among authors: knutsen t. Genes Chromosomes Cancer. 2012 Apr;51(4):353-74. doi: 10.1002/gcc.21921. Epub 2011 Dec 8. Genes Chromosomes Cancer. 2012. PMID: 22161874 Free PMC article.
Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL.
Knutsen T, Mickley LA, Ried T, Green ED, du Manoir S, Schröck E, Macville M, Ning Y, Robey R, Polymeropoulos M, Torres R, Fojo T. Knutsen T, et al. Genes Chromosomes Cancer. 1998 Sep;23(1):44-54. doi: 10.1002/(sici)1098-2264(199809)23:1<44::aid-gcc7>3.0.co;2-6. Genes Chromosomes Cancer. 1998. PMID: 9713996
103 results