Establishment of an oriP replicon is dependent upon an infrequent, epigenetic event.
Leight ER, Sugden B.
Leight ER, et al. Among authors: sugden b.
Mol Cell Biol. 2001 Jul;21(13):4149-61. doi: 10.1128/MCB.21.13.4149-4161.2001.
Mol Cell Biol. 2001.
PMID: 11390644
Free PMC article.
Plasmids containing oriP, the latent origin of replication for Epstein-Barr virus, support efficient replication in selected cell clones when the viral protein EBNA-1 is provided, being lost at a rate of 2 to 4% per cell generation after removal of selection (A. L. Kirchmaier and …
Plasmids containing oriP, the latent origin of replication for Epstein-Barr virus, support efficient replication in selected cell clones whe …