Schwartz G - Search Results

1

A phase I and pharmacokinetic study of 1843U89, a noncompetitive inhibitor of thymidylate synthase, in patients with advanced solid malignancies.

Schwartz G, Johnson TR, Goetz A, Burris H, Smetzer L, Lampkin T, Sailstad J, Hohneker JA, Von Hoff DD, Rowinsky EK. Schwartz G, et al. Clin Cancer Res. 2001 Jul;7(7):1901-11. Clin Cancer Res. 2001. PMID: 11448903 Clinical Trial.

2

A pilot clinical/pharmacological study of the protein kinase C-specific inhibitor safingol alone and in combination with doxorubicin.

Schwartz GK, Ward D, Saltz L, Casper ES, Spiess T, Mullen E, Woodworth J, Venuti R, Zervos P, Storniolo AM, Kelsen DP. Schwartz GK, et al. Clin Cancer Res. 1997 Apr;3(4):537-43. Clin Cancer Res. 1997. PMID: 9815717 Clinical Trial.

3

DX-8951f, a hexacyclic camptothecin analog, on a daily-times-five schedule: a phase I and pharmacokinetic study in patients with advanced solid malignancies.

Rowinsky EK, Johnson TR, Geyer CE Jr, Hammond LA, Eckhardt SG, Drengler R, Smetzer L, Coyle J, Rizzo J, Schwartz G, Tolcher A, Von Hoff DD, De Jager RL. Rowinsky EK, et al. Among authors: schwartz g. J Clin Oncol. 2000 Sep;18(17):3151-63. doi: 10.1200/JCO.2000.18.17.3151. J Clin Oncol. 2000. PMID: 10963644 Clinical Trial.

4

Pharmacokinetics and bioequivalence of a combined oral formulation of eniluracil, an inactivator of dihydropyrimidine dehydrogenase, and 5-fluorouracil in patients with advanced solid malignancies.

Ochoa L, Hurwitz HI, Wilding G, Cohen D, Thomas JP, Schwartz G, Monroe P, Petros WP, Ertel VP, Hsieh A, Hoffman C, Drengler R, Magnum S, Rowinsky EK. Ochoa L, et al. Among authors: schwartz g. Ann Oncol. 2000 Oct;11(10):1313-22. doi: 10.1023/a:1008379802642. Ann Oncol. 2000. PMID: 11106122 Free article. Clinical Trial.

5

Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma.

Schwartz GK, Ilson D, Saltz L, O'Reilly E, Tong W, Maslak P, Werner J, Perkins P, Stoltz M, Kelsen D. Schwartz GK, et al. J Clin Oncol. 2001 Apr 1;19(7):1985-92. doi: 10.1200/JCO.2001.19.7.1985. J Clin Oncol. 2001. PMID: 11283131 Clinical Trial.

6

Phase I and pharmacokinetic study of BMS-184476, a taxane with greater potency and solubility than paclitaxel.

Hidalgo M, Aylesworth C, Hammond LA, Britten CD, Weiss G, Stephenson J Jr, Schwartz G, Patnaik A, Smith L, Molpus K, Felton S, Gupta E, Ferrante KJ, Tortora A, Sonnichsen DS, Skillings J, Rowinsky EK. Hidalgo M, et al. Among authors: schwartz g. J Clin Oncol. 2001 May 1;19(9):2493-503. doi: 10.1200/JCO.2001.19.9.2493. J Clin Oncol. 2001. PMID: 11331328 Clinical Trial.

7

Phase I and pharmacokinetic study of NSC 655649, a rebeccamycin analog with topoisomerase inhibitory properties.

Tolcher AW, Eckhardt SG, Kuhn J, Hammond L, Weiss G, Rizzo J, Aylesworth C, Hidalgo M, Patnaik A, Schwartz G, Felton S, Campbell E, Rowinsky EK. Tolcher AW, et al. Among authors: schwartz g. J Clin Oncol. 2001 Jun 1;19(11):2937-47. doi: 10.1200/JCO.2001.19.11.2937. J Clin Oncol. 2001. PMID: 11387367 Clinical Trial.

8

Phase I study of topoisomerase I inhibitor exatecan mesylate (DX-8951f) given as weekly 24-hour infusions three of every four weeks.

Sharma S, Kemeny N, Schwartz GK, Kelsen D, O'Reilly E, Ilson D, Coyle J, De Jager RL, Ducharme MP, Kleban S, Hollywood E, Saltz LB. Sharma S, et al. Among authors: schwartz gk. Clin Cancer Res. 2001 Dec;7(12):3963-70. Clin Cancer Res. 2001. PMID: 11751488 Clinical Trial.

9

Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules.

Tolcher AW, Gerson SL, Denis L, Geyer C, Hammond LA, Patnaik A, Goetz AD, Schwartz G, Edwards T, Reyderman L, Statkevich P, Cutler DL, Rowinsky EK. Tolcher AW, et al. Among authors: schwartz g. Br J Cancer. 2003 Apr 7;88(7):1004-11. doi: 10.1038/sj.bjc.6600827. Br J Cancer. 2003. PMID: 12671695 Free PMC article.

10

Phase I and pharmacokinetic study of LY293111, an orally bioavailable LTB4 receptor antagonist, in patients with advanced solid tumors.

Schwartz GK, Weitzman A, O'Reilly E, Brail L, de Alwis DP, Cleverly A, Barile-Thiem B, Vinciguerra V, Budman DR. Schwartz GK, et al. J Clin Oncol. 2005 Aug 10;23(23):5365-73. doi: 10.1200/JCO.2005.02.766. Epub 2005 Jun 6. J Clin Oncol. 2005. PMID: 15939925 Clinical Trial.

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