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A rational approach to the design of selective substrates and potent nontransportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). new glutamate and aspartate analogues as potential neuroprotective agents.
Campiani G, De Angelis M, Armaroli S, Fattorusso C, Catalanotti B, Ramunno A, Nacci V, Novellino E, Grewer C, Ionescu D, Rauen T, Griffiths R, Sinclair C, Fumagalli E, Mennini T. Campiani G, et al. Among authors: fumagalli e. J Med Chem. 2001 Aug 2;44(16):2507-10. doi: 10.1021/jm015509z. J Med Chem. 2001. PMID: 11472204 No abstract available.
Characterization of the 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent, and subtype-selective AMPA receptor full agonist with partial desensitization properties.
Campiani G, Morelli E, Nacci V, Fattorusso C, Ramunno A, Novellino E, Greenwood J, Liljefors T, Griffiths R, Sinclair C, Reavy H, Kristensen AS, Pickering DS, Schousboe A, Cagnotto A, Fumagalli E, Mennini T. Campiani G, et al. Among authors: fumagalli e. J Med Chem. 2001 Dec 20;44(26):4501-4. doi: 10.1021/jm015552m. J Med Chem. 2001. PMID: 11741469
Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.
Campiani G, Butini S, Trotta F, Fattorusso C, Catalanotti B, Aiello F, Gemma S, Nacci V, Novellino E, Stark JA, Cagnotto A, Fumagalli E, Carnovali F, Cervo L, Mennini T. Campiani G, et al. Among authors: fumagalli e. J Med Chem. 2003 Aug 28;46(18):3822-39. doi: 10.1021/jm0211220. J Med Chem. 2003. PMID: 12930145
Neuroprotective effects of the novel glutamate transporter inhibitor (-)-3-hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]-isoxazole-4-carboxylic acid, which preferentially inhibits reverse transport (glutamate release) compared with glutamate reuptake.
Colleoni S, Jensen AA, Landucci E, Fumagalli E, Conti P, Pinto A, De Amici M, Pellegrini-Giampietro DE, De Micheli C, Mennini T, Gobbi M. Colleoni S, et al. Among authors: fumagalli e. J Pharmacol Exp Ther. 2008 Aug;326(2):646-56. doi: 10.1124/jpet.107.135251. Epub 2008 May 1. J Pharmacol Exp Ther. 2008. PMID: 18451317
149 results