Dirsch VM - Search Results

1

Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2.

Dirsch VM, Stuppner H, Vollmar AM. Dirsch VM, et al. Cancer Res. 2001 Aug 1;61(15):5817-23. Cancer Res. 2001. PMID: 11479221

2

Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix.

Dirsch VM, Müller IM, Eichhorst ST, Pettit GR, Kamano Y, Inoue M, Xu JP, Ichihara Y, Wanner G, Vollmar AM. Dirsch VM, et al. Cancer Res. 2003 Dec 15;63(24):8869-76. Cancer Res. 2003. PMID: 14695204

3

Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation.

Hoffmann R, von Schwarzenberg K, López-Antón N, Rudy A, Wanner G, Dirsch VM, Vollmar AM. Hoffmann R, et al. Among authors: dirsch vm. Biochem Pharmacol. 2011 Sep 1;82(5):453-63. doi: 10.1016/j.bcp.2011.05.029. Epub 2011 Jun 2. Biochem Pharmacol. 2011. PMID: 21669190 Free article.

4

Ajoene, an experimental anti-leukemic drug: mechanism of cell death.

Dirsch VM, Antlsperger DS, Hentze H, Vollmar AM. Dirsch VM, et al. Leukemia. 2002 Jan;16(1):74-83. doi: 10.1038/sj.leu.2402337. Leukemia. 2002. PMID: 11840266

5

Role of Smac in cephalostatin-induced cell death.

Rudy A, López-Antón N, Barth N, Pettit GR, Dirsch VM, Schulze-Osthoff K, Rehm M, Prehn JH, Vogler M, Fulda S, Vollmar AM. Rudy A, et al. Among authors: dirsch vm. Cell Death Differ. 2008 Dec;15(12):1930-40. doi: 10.1038/cdd.2008.125. Epub 2008 Sep 19. Cell Death Differ. 2008. PMID: 18806754

6

Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells.

Haider UG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Haider UG, et al. Among authors: dirsch vm. Mol Pharmacol. 2002 Oct;62(4):772-7. doi: 10.1124/mol.62.4.772. Mol Pharmacol. 2002. PMID: 12237323

7

Ajoene-induced cell death in human promyeloleukemic cells does not require JNK but is amplified by the inhibition of ERK.

Antlsperger DS, Dirsch VM, Ferreira D, Su JL, Kuo ML, Vollmar AM. Antlsperger DS, et al. Among authors: dirsch vm. Oncogene. 2003 Jan 30;22(4):582-9. doi: 10.1038/sj.onc.1206161. Oncogene. 2003. PMID: 12555071

8

Apoptosis signaling triggered by the marine alkaloid ascididemin is routed via caspase-2 and JNK to mitochondria.

Dirsch VM, Kirschke SO, Estermeier M, Steffan B, Vollmar AM. Dirsch VM, et al. Oncogene. 2004 Feb 26;23(8):1586-93. doi: 10.1038/sj.onc.1207281. Oncogene. 2004. PMID: 14716300

9

Cephalostatin 1 inactivates Bcl-2 by hyperphosphorylation independent of M-phase arrest and DNA damage.

Müller IM, Dirsch VM, Rudy A, López-Antón N, Pettit GR, Vollmar AM. Müller IM, et al. Among authors: dirsch vm. Mol Pharmacol. 2005 May;67(5):1684-9. doi: 10.1124/mol.104.004234. Epub 2005 Feb 9. Mol Pharmacol. 2005. PMID: 15703383

10

The marine product cephalostatin 1 activates an endoplasmic reticulum stress-specific and apoptosome-independent apoptotic signaling pathway.

López-Antón N, Rudy A, Barth N, Schmitz ML, Pettit GR, Schulze-Osthoff K, Dirsch VM, Vollmar AM. López-Antón N, et al. Among authors: dirsch vm. J Biol Chem. 2006 Nov 3;281(44):33078-86. doi: 10.1074/jbc.M607904200. Epub 2006 Aug 31. J Biol Chem. 2006. PMID: 16945918 Free article.

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