Brownlee M - Search Results

1

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action.

Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. Berg AH, et al. Among authors: brownlee m. Nat Med. 2001 Aug;7(8):947-53. doi: 10.1038/90992. Nat Med. 2001. PMID: 11479628

2

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity.

Pajvani UB, Du X, Combs TP, Berg AH, Rajala MW, Schulthess T, Engel J, Brownlee M, Scherer PE. Pajvani UB, et al. Among authors: brownlee m. J Biol Chem. 2003 Mar 14;278(11):9073-85. doi: 10.1074/jbc.M207198200. Epub 2002 Dec 20. J Biol Chem. 2003. PMID: 12496257 Free article.

3

The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.

Lin Y, Berg AH, Iyengar P, Lam TK, Giacca A, Combs TP, Rajala MW, Du X, Rollman B, Li W, Hawkins M, Barzilai N, Rhodes CJ, Fantus IG, Brownlee M, Scherer PE. Lin Y, et al. Among authors: brownlee m. J Biol Chem. 2005 Feb 11;280(6):4617-26. doi: 10.1074/jbc.M411863200. Epub 2004 Nov 9. J Biol Chem. 2005. PMID: 15536073 Free article.

4

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage.

Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M. Nishikawa T, et al. Among authors: brownlee m. Nature. 2000 Apr 13;404(6779):787-90. doi: 10.1038/35008121. Nature. 2000. PMID: 10783895

5

PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation.

Wang ZV, Mu J, Schraw TD, Gautron L, Elmquist JK, Zhang BB, Brownlee M, Scherer PE. Wang ZV, et al. Among authors: brownlee m. Diabetes. 2008 Aug;57(8):2137-48. doi: 10.2337/db07-1631. Epub 2008 May 9. Diabetes. 2008. PMID: 18469203 Free PMC article.

6

Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A.

Yamagishi SI, Edelstein D, Du XL, Kaneda Y, Guzmán M, Brownlee M. Yamagishi SI, et al. Among authors: brownlee m. J Biol Chem. 2001 Jul 6;276(27):25096-100. doi: 10.1074/jbc.M007383200. Epub 2001 May 7. J Biol Chem. 2001. PMID: 11342529 Free article.

7

Hyperglycemia potentiates collagen-induced platelet activation through mitochondrial superoxide overproduction.

Yamagishi SI, Edelstein D, Du XL, Brownlee M. Yamagishi SI, et al. Among authors: brownlee m. Diabetes. 2001 Jun;50(6):1491-4. doi: 10.2337/diabetes.50.6.1491. Diabetes. 2001. PMID: 11375352

8

Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site.

Du XL, Edelstein D, Dimmeler S, Ju Q, Sui C, Brownlee M. Du XL, et al. Among authors: brownlee m. J Clin Invest. 2001 Nov;108(9):1341-8. doi: 10.1172/JCI11235. J Clin Invest. 2001. PMID: 11696579 Free PMC article.

9

Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation.

Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M. Du X, et al. Among authors: brownlee m. J Clin Invest. 2006 Apr;116(4):1071-80. doi: 10.1172/JCI23354. Epub 2006 Mar 9. J Clin Invest. 2006. PMID: 16528409 Free PMC article.

10

Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.

Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M. Du XL, et al. Among authors: brownlee m. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12222-6. doi: 10.1073/pnas.97.22.12222. Proc Natl Acad Sci U S A. 2000. PMID: 11050244 Free PMC article.

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