Kerr EM - Search Results

1

Attributes of gammadelta intraepithelial lymphocytes as suggested by their transcriptional profile.

Fahrer AM, Konigshofer Y, Kerr EM, Ghandour G, Mack DH, Davis MM, Chien YH. Fahrer AM, et al. Among authors: kerr em. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10261-6. doi: 10.1073/pnas.171320798. Proc Natl Acad Sci U S A. 2001. PMID: 11526237 Free PMC article.

2

Activation and differentiation requirements of primary T cells in vitro.

Sagerström CG, Kerr EM, Allison JP, Davis MM. Sagerström CG, et al. Among authors: kerr em. Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):8987-91. doi: 10.1073/pnas.90.19.8987. Proc Natl Acad Sci U S A. 1993. PMID: 8415642 Free PMC article.

3

The pseudo-caspase FLIP(L) regulates cell fate following p53 activation.

Lees A, McIntyre AJ, Crawford NT, Falcone F, McCann C, Holohan C, Quinn GP, Roberts JZ, Sessler T, Gallagher PF, Gregg GMA, McAllister K, McLaughlin KM, Allen WL, Egan LJ, Ryan AE, Labonte-Wilson MJ, Dunne PD, Wappett M, Coyle VM, Johnston PG, Kerr EM, Longley DB, McDade SS. Lees A, et al. Among authors: kerr em. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17808-17819. doi: 10.1073/pnas.2001520117. Epub 2020 Jul 13. Proc Natl Acad Sci U S A. 2020. PMID: 32661168 Free PMC article.

4

Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent.

Hurwitz JL, Stasik I, Kerr EM, Holohan C, Redmond KM, McLaughlin KM, Busacca S, Barbone D, Broaddus VC, Gray SG, O'Byrne KJ, Johnston PG, Fennell DA, Longley DB. Hurwitz JL, et al. Among authors: kerr em. Eur J Cancer. 2012 May;48(7):1096-107. doi: 10.1016/j.ejca.2011.11.009. Epub 2011 Dec 10. Eur J Cancer. 2012. PMID: 22154545

5

Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis.

Kerr E, Holohan C, McLaughlin KM, Majkut J, Dolan S, Redmond K, Riley J, McLaughlin K, Stasik I, Crudden M, Van Schaeybroeck S, Fenning C, O'Connor R, Kiely P, Sgobba M, Haigh D, Johnston PG, Longley DB. Kerr E, et al. Cell Death Differ. 2012 Aug;19(8):1317-27. doi: 10.1038/cdd.2012.8. Epub 2012 Feb 10. Cell Death Differ. 2012. PMID: 22322857 Free PMC article.

6

Differential affinity of FLIP and procaspase 8 for FADD's DED binding surfaces regulates DISC assembly.

Majkut J, Sgobba M, Holohan C, Crawford N, Logan AE, Kerr E, Higgins CA, Redmond KL, Riley JS, Stasik I, Fennell DA, Van Schaeybroeck S, Haider S, Johnston PG, Haigh D, Longley DB. Majkut J, et al. Nat Commun. 2014 Feb 28;5:3350. doi: 10.1038/ncomms4350. Nat Commun. 2014. PMID: 24577104 Free PMC article.

7

Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer.

Crawford N, Stott KJ, Sessler T, McCann C, McDaid W, Lees A, Latimer C, Fox JP, Munck JM, Smyth T, Shah A, Martins V, Lawler M, Dunne PD, Kerr EM, McDade SS, Coyle VM, Longley DB. Crawford N, et al. Among authors: kerr em. Mol Cancer Ther. 2021 Sep;20(9):1627-1639. doi: 10.1158/1535-7163.MCT-20-1050. Epub 2021 Aug 13. Mol Cancer Ther. 2021. PMID: 34389694 Free PMC article.

8

Metabolic Reprogramming: A Friend or Foe to Cancer Therapy?

McCann C, Kerr EM. McCann C, et al. Among authors: kerr em. Cancers (Basel). 2021 Jul 3;13(13):3351. doi: 10.3390/cancers13133351. Cancers (Basel). 2021. PMID: 34283054 Free PMC article. Review.

9

Rerouting the drug response: Overcoming metabolic adaptation in KRAS-mutant cancers.

Moss DY, McCann C, Kerr EM. Moss DY, et al. Among authors: kerr em. Sci Signal. 2022 Oct 18;15(756):eabj3490. doi: 10.1126/scisignal.abj3490. Epub 2022 Oct 18. Sci Signal. 2022. PMID: 36256706 Review.

10

Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.

Corry SM, McCorry AM, Lannagan TR, Leonard NA, Fisher NC, Byrne RM, Tsantoulis P, Cortes-Lavaud X, Amirkhah R, Redmond KL, McCooey AJ, Malla SB, Rogan E, Sakhnevych S, Gillespie MA, White M, Richman SD, Jackstadt RF, Campbell AD, Maguire S; S:CORT and ACRCelerate consortia; McDade SS, Longley DB, Loughrey MB, Coleman HG, Kerr EM, Tejpar S, Maughan T, Leedham SJ, Small DM, Ryan AE, Sansom OJ, Lawler M, Dunne PD. Corry SM, et al. Among authors: kerr em. Gut. 2022 Dec;71(12):2502-2517. doi: 10.1136/gutjnl-2021-326183. Epub 2022 Apr 27. Gut. 2022. PMID: 35477539 Free PMC article.

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