Seiki M - Search Results

1

Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion.

Itoh Y, Takamura A, Ito N, Maru Y, Sato H, Suenaga N, Aoki T, Seiki M. Itoh Y, et al. Among authors: seiki m. EMBO J. 2001 Sep 3;20(17):4782-93. doi: 10.1093/emboj/20.17.4782. EMBO J. 2001. PMID: 11532942 Free PMC article.

2

CD44 directs membrane-type 1 matrix metalloproteinase to lamellipodia by associating with its hemopexin-like domain.

Mori H, Tomari T, Koshikawa N, Kajita M, Itoh Y, Sato H, Tojo H, Yana I, Seiki M. Mori H, et al. Among authors: seiki m. EMBO J. 2002 Aug 1;21(15):3949-59. doi: 10.1093/emboj/cdf411. EMBO J. 2002. PMID: 12145196 Free PMC article.

3

Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: importance of MT1-MMP as a therapeutic target for invasive tumors.

Ueda J, Kajita M, Suenaga N, Fujii K, Seiki M. Ueda J, et al. Among authors: seiki m. Oncogene. 2003 Nov 27;22(54):8716-22. doi: 10.1038/sj.onc.1206962. Oncogene. 2003. PMID: 14647466

4

Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.

Uekita T, Gotoh I, Kinoshita T, Itoh Y, Sato H, Shiomi T, Okada Y, Seiki M. Uekita T, et al. Among authors: seiki m. J Biol Chem. 2004 Mar 26;279(13):12734-43. doi: 10.1074/jbc.M309957200. Epub 2004 Jan 12. J Biol Chem. 2004. PMID: 14718544 Free article.

5

MT1-MMP: an enzyme with multidimensional regulation.

Itoh Y, Seiki M. Itoh Y, et al. Among authors: seiki m. Trends Biochem Sci. 2004 Jun;29(6):285-9. doi: 10.1016/j.tibs.2004.04.001. Trends Biochem Sci. 2004. PMID: 15276180

6

CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase.

Suenaga N, Mori H, Itoh Y, Seiki M. Suenaga N, et al. Among authors: seiki m. Oncogene. 2005 Jan 27;24(5):859-68. doi: 10.1038/sj.onc.1208258. Oncogene. 2005. PMID: 15558018

7

MT1-MMP: a potent modifier of pericellular microenvironment.

Itoh Y, Seiki M. Itoh Y, et al. Among authors: seiki m. J Cell Physiol. 2006 Jan;206(1):1-8. doi: 10.1002/jcp.20431. J Cell Physiol. 2006. PMID: 15920734 Review.

8

Competitive disruption of the tumor-promoting function of membrane type 1 matrix metalloproteinase/matrix metalloproteinase-14 in vivo.

Nonaka T, Nishibashi K, Itoh Y, Yana I, Seiki M. Nonaka T, et al. Among authors: seiki m. Mol Cancer Ther. 2005 Aug;4(8):1157-66. doi: 10.1158/1535-7163.MCT-05-0127. Mol Cancer Ther. 2005. PMID: 16093431 Free article.

9

Cell surface collagenolysis requires homodimerization of the membrane-bound collagenase MT1-MMP.

Itoh Y, Ito N, Nagase H, Evans RD, Bird SA, Seiki M. Itoh Y, et al. Among authors: seiki m. Mol Biol Cell. 2006 Dec;17(12):5390-9. doi: 10.1091/mbc.e06-08-0740. Epub 2006 Oct 18. Mol Biol Cell. 2006. PMID: 17050733 Free PMC article.

10

The second dimer interface of MT1-MMP, the transmembrane domain, is essential for ProMMP-2 activation on the cell surface.

Itoh Y, Ito N, Nagase H, Seiki M. Itoh Y, et al. Among authors: seiki m. J Biol Chem. 2008 May 9;283(19):13053-62. doi: 10.1074/jbc.M709327200. Epub 2008 Mar 12. J Biol Chem. 2008. PMID: 18337248 Free PMC article.

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