Palsson-McDermott EM - Search Results

1

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction.

Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA. Fitzgerald KA, et al. Nature. 2001 Sep 6;413(6851):78-83. doi: 10.1038/35092578. Nature. 2001. PMID: 11544529

2

Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4.

Pålsson-McDermott EM, O'Neill LA. Pålsson-McDermott EM, et al. Immunology. 2004 Oct;113(2):153-62. doi: 10.1111/j.1365-2567.2004.01976.x. Immunology. 2004. PMID: 15379975 Free PMC article. Review.

3

Trif-related adapter molecule is phosphorylated by PKC{epsilon} during Toll-like receptor 4 signaling.

McGettrick AF, Brint EK, Palsson-McDermott EM, Rowe DC, Golenbock DT, Gay NJ, Fitzgerald KA, O'Neill LA. McGettrick AF, et al. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9196-201. doi: 10.1073/pnas.0600462103. Epub 2006 Jun 6. Proc Natl Acad Sci U S A. 2006. PMID: 16757566 Free PMC article.

4

NF-kappaB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1.

Miggin SM, Pålsson-McDermott E, Dunne A, Jefferies C, Pinteaux E, Banahan K, Murphy C, Moynagh P, Yamamoto M, Akira S, Rothwell N, Golenbock D, Fitzgerald KA, O'Neill LA. Miggin SM, et al. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3372-7. doi: 10.1073/pnas.0608100104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360653 Free PMC article.

5

The potential of targeting Toll-like receptor 2 in autoimmune and inflammatory diseases.

Pålsson-McDermott EM, O'Neill LA. Pålsson-McDermott EM, et al. Ir J Med Sci. 2007 Dec;176(4):253-60. doi: 10.1007/s11845-007-0103-1. Epub 2007 Nov 15. Ir J Med Sci. 2007. PMID: 18004613 Review.

6

Building an immune system from nine domains.

Pålsson-McDermott EM, O'Neill LA. Pålsson-McDermott EM, et al. Biochem Soc Trans. 2007 Dec;35(Pt 6):1437-44. doi: 10.1042/BST0351437. Biochem Soc Trans. 2007. PMID: 18031241 Review.

7

Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like receptor-3 and -4 by targeting TBK1 activation.

McCoy CE, Carpenter S, Pålsson-McDermott EM, Gearing LJ, O'Neill LA. McCoy CE, et al. J Biol Chem. 2008 May 23;283(21):14277-85. doi: 10.1074/jbc.M709731200. Epub 2008 Mar 20. J Biol Chem. 2008. PMID: 18356163 Free article.

8

TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.

Palsson-McDermott EM, Doyle SL, McGettrick AF, Hardy M, Husebye H, Banahan K, Gong M, Golenbock D, Espevik T, O'Neill LA. Palsson-McDermott EM, et al. Nat Immunol. 2009 Jun;10(6):579-86. doi: 10.1038/ni.1727. Epub 2009 May 3. Nat Immunol. 2009. PMID: 19412184

9

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21.

Sheedy FJ, Palsson-McDermott E, Hennessy EJ, Martin C, O'Leary JJ, Ruan Q, Johnson DS, Chen Y, O'Neill LA. Sheedy FJ, et al. Nat Immunol. 2010 Feb;11(2):141-7. doi: 10.1038/ni.1828. Epub 2009 Nov 29. Nat Immunol. 2010. PMID: 19946272

10

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, Haneklaus M, Caffrey BE, Pierce K, Walmsley S, Beasley FC, Cummins E, Nizet V, Whyte M, Taylor CT, Lin H, Masters SL, Gottlieb E, Kelly VP, Clish C, Auron PE, Xavier RJ, O'Neill LA. Tannahill GM, et al. Nature. 2013 Apr 11;496(7444):238-42. doi: 10.1038/nature11986. Epub 2013 Mar 24. Nature. 2013. PMID: 23535595 Free PMC article.

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