Friel EC - Search Results

1

Effects of 18-hydroxylated steroids on corticosteroid production by human aldosterone synthase and 11beta-hydroxylase.

Fisher A, Friel EC, Bernhardt R, Gomez-Sanchez C, Connell JM, Fraser R, Davies E. Fisher A, et al. Among authors: friel ec. J Clin Endocrinol Metab. 2001 Sep;86(9):4326-9. doi: 10.1210/jcem.86.9.7797. J Clin Endocrinol Metab. 2001. PMID: 11549669

2

Effects of genetic variation in the aldosterone synthase (CYP11B2) gene on enzyme function.

Holloway CD, MacKenzie SM, Fraser R, Miller S, Barr M, Wilkinson D, Forbes GH, Friel E, Connell JM, Davies E. Holloway CD, et al. Clin Endocrinol (Oxf). 2009 Mar;70(3):363-71. doi: 10.1111/j.1365-2265.2008.03383.x. Epub 2008 Aug 15. Clin Endocrinol (Oxf). 2009. PMID: 18710464

3

The impact of polymorphisms in the gene encoding aldosterone synthase (CYP11B2) on steroid synthesis and blood pressure regulation.

Connell JM, Fraser R, MacKenzie SM, Friel EC, Ingram MC, Holloway CD, Davies E. Connell JM, et al. Among authors: friel ec. Mol Cell Endocrinol. 2004 Mar 31;217(1-2):243-7. doi: 10.1016/j.mce.2003.10.025. Mol Cell Endocrinol. 2004. PMID: 15134824 Review.

4

Aldosterone synthase gene variation and adrenocortical response to sodium status, angiotensin II and ACTH in normal male subjects.

Kennon B, Ingram MC, Friel EC, Anderson NH, MacKenzie SM, Davies E, Shakerdi L, Wallace AM, Fraser R, Connell JM. Kennon B, et al. Among authors: friel ec. Clin Endocrinol (Oxf). 2004 Aug;61(2):174-81. doi: 10.1111/j.1365-2265.2004.02073.x. Clin Endocrinol (Oxf). 2004. PMID: 15272911 Clinical Trial.

5

Studies on the origin of circulating 18-hydroxycortisol and 18-oxocortisol in normal human subjects.

Freel EM, Shakerdi LA, Friel EC, Wallace AM, Davies E, Fraser R, Connell JM. Freel EM, et al. Among authors: friel ec. J Clin Endocrinol Metab. 2004 Sep;89(9):4628-33. doi: 10.1210/jc.2004-0379. J Clin Endocrinol Metab. 2004. PMID: 15356073 Free PMC article.

6

Functional effects of genetic variants in the 11beta-hydroxylase (CYP11B1) gene.

Barr M, MacKenzie SM, Wilkinson DM, Holloway CD, Friel EC, Miller S, MacDonald T, Fraser R, Connell JM, Davies E. Barr M, et al. Among authors: friel ec. Clin Endocrinol (Oxf). 2006 Dec;65(6):816-25. doi: 10.1111/j.1365-2265.2006.02673.x. Clin Endocrinol (Oxf). 2006. PMID: 17121536

7

Polymorphic differences from normal in the aldosterone synthase gene (CYP11B2) in patients with primary hyperaldosteronism and adrenal tumour (Conn's syndrome).

Inglis GC, Plouin PF, Friel EC, Davies E, Fraser R, Connell JM. Inglis GC, et al. Among authors: friel ec. Clin Endocrinol (Oxf). 2001 Jun;54(6):725-30. doi: 10.1046/j.1365-2265.2001.01287.x. Clin Endocrinol (Oxf). 2001. PMID: 11422106

8

An influence of variation in the aldosterone synthase gene (CYP11B2) on corticosteroid responses to ACTH in normal human subjects.

Davies E, Holloway CD, Ingram MC, Friel EC, Inglis GC, Swan L, Hillis WS, Fraser R, Connell JM. Davies E, et al. Among authors: friel ec. Clin Endocrinol (Oxf). 2001 Jun;54(6):813-7. doi: 10.1046/j.1365-2265.2001.01264.x. Clin Endocrinol (Oxf). 2001. PMID: 11422117 Clinical Trial.

9

Phenotypic consequences of variation across the aldosterone synthase and 11-beta hydroxylase locus in a hypertensive cohort: data from the MRC BRIGHT Study.

Freel EM, Ingram M, Friel EC, Fraser R, Brown M, Samani NJ, Caulfield M, Munroe P, Farrall M, Webster J, Clayton D, Dominiczak AF, Davies E, Connell JM. Freel EM, et al. Among authors: friel ec. Clin Endocrinol (Oxf). 2007 Dec;67(6):832-8. doi: 10.1111/j.1365-2265.2007.02971.x. Epub 2007 Jul 25. Clin Endocrinol (Oxf). 2007. PMID: 17651452

10

Polymorphic variation in the 11beta-hydroxylase gene associates with reduced 11-hydroxylase efficiency.

Barr M, MacKenzie SM, Friel EC, Holloway CD, Wilkinson DM, Brain NJ, Ingram MC, Fraser R, Brown M, Samani NJ, Caulfield M, Munroe PB, Farrall M, Webster J, Clayton D, Dominiczak AF, Connell JM, Davies E. Barr M, et al. Among authors: friel ec. Hypertension. 2007 Jan;49(1):113-9. doi: 10.1161/01.HYP.0000249904.93940.7a. Epub 2006 Oct 30. Hypertension. 2007. PMID: 17075029

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