De Clercq E - Search Results

1

AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.

Matthys P, Hatse S, Vermeire K, Wuyts A, Bridger G, Henson GW, De Clercq E, Billiau A, Schols D. Matthys P, et al. Among authors: de clercq e. J Immunol. 2001 Oct 15;167(8):4686-92. doi: 10.4049/jimmunol.167.8.4686. J Immunol. 2001. PMID: 11591799

2

Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4.

Schols D, Struyf S, Van Damme J, Esté JA, Henson G, De Clercq E. Schols D, et al. Among authors: de clercq e. J Exp Med. 1997 Oct 20;186(8):1383-8. doi: 10.1084/jem.186.8.1383. J Exp Med. 1997. PMID: 9334378 Free PMC article.

3

Enhanced anti-HIV-1 activity and altered chemotactic potency of NH2-terminally processed macrophage-derived chemokine (MDC) imply an additional MDC receptor.

Struyf S, Proost P, Sozzani S, Mantovani A, Wuyts A, De Clercq E, Schols D, Van Damme J. Struyf S, et al. Among authors: de clercq e. J Immunol. 1998 Sep 15;161(6):2672-5. J Immunol. 1998. PMID: 9743322

4

The simian immunodeficiency virus mnd(GB-1) strain uses CXCR4, not CCR5, as coreceptor for entry in human cells.

Schols D, De Clercq E. Schols D, et al. Among authors: de clercq e. J Gen Virol. 1998 Sep;79 ( Pt 9):2203-5. doi: 10.1099/0022-1317-79-9-2203. J Gen Virol. 1998. PMID: 9747729

5

CXC-chemokine receptor 4 is not a coreceptor for human herpesvirus 7 entry into CD4(+) T cells.

Zhang Y, Hatse S, De Clercq E, Schols D. Zhang Y, et al. Among authors: de clercq e. J Virol. 2000 Feb;74(4):2011-6. doi: 10.1128/jvi.74.4.2011-2016.2000. J Virol. 2000. PMID: 10644374 Free PMC article.

6

Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.

Hatse S, Princen K, Gerlach LO, Bridger G, Henson G, De Clercq E, Schwartz TW, Schols D. Hatse S, et al. Among authors: de clercq e. Mol Pharmacol. 2001 Jul;60(1):164-73. doi: 10.1124/mol.60.1.164. Mol Pharmacol. 2001. PMID: 11408611

7

Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists.

De Clercq E, Schols D. De Clercq E, et al. Antivir Chem Chemother. 2001;12 Suppl 1:19-31. Antivir Chem Chemother. 2001. PMID: 11594685

8

X4 HIV-1 induces neuroblastoma cell death by interference with CXCL12/CXCR4 interaction.

Hatse S, Bridger G, de Clercq E, Schols D. Hatse S, et al. Among authors: de clercq e. Cell Mol Biol (Noisy-le-grand). 2003;49 Online Pub:OL443-52. Cell Mol Biol (Noisy-le-grand). 2003. PMID: 14995074

9

Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4.

Schols D, Esté JA, Henson G, De Clercq E. Schols D, et al. Among authors: de clercq e. Antiviral Res. 1997 Aug;35(3):147-56. doi: 10.1016/s0166-3542(97)00025-9. Antiviral Res. 1997. PMID: 9298754

10

T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor use.

Schols D, Esté JA, Cabrera C, De Clercq E. Schols D, et al. Among authors: de clercq e. J Virol. 1998 May;72(5):4032-7. doi: 10.1128/JVI.72.5.4032-4037.1998. J Virol. 1998. PMID: 9557691 Free PMC article.

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