Askew DJ - Search Results

1

SERPINB12 is a novel member of the human ov-serpin family that is widely expressed and inhibits trypsin-like serine proteinases.

Askew YS, Pak SC, Luke CJ, Askew DJ, Cataltepe S, Mills DR, Kato H, Lehoczky J, Dewar K, Birren B, Silverman GA. Askew YS, et al. Among authors: askew dj. J Biol Chem. 2001 Dec 28;276(52):49320-30. doi: 10.1074/jbc.M108879200. Epub 2001 Oct 16. J Biol Chem. 2001. PMID: 11604408 Free article.

2

The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases.

Al-Khunaizi M, Luke CJ, Askew YS, Pak SC, Askew DJ, Cataltepe S, Miller D, Mills DR, Tsu C, Brömme D, Irving JA, Whisstock JC, Silverman GA. Al-Khunaizi M, et al. Among authors: askew dj, askew ys. Biochemistry. 2002 Mar 5;41(9):3189-99. doi: 10.1021/bi015999x. Biochemistry. 2002. PMID: 11863458

3

SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins.

Pak SC, Kumar V, Tsu C, Luke CJ, Askew YS, Askew DJ, Mills DR, Brömme D, Silverman GA. Pak SC, et al. Among authors: askew dj, askew ys. J Biol Chem. 2004 Apr 9;279(15):15448-59. doi: 10.1074/jbc.M400261200. Epub 2004 Jan 22. J Biol Chem. 2004. PMID: 14739286 Free article.

4

The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases.

Askew DJ, Askew YS, Kato Y, Luke CJ, Pak SC, Brömme D, Silverman GA. Askew DJ, et al. Among authors: askew ys. Genomics. 2004 Jul;84(1):166-75. doi: 10.1016/j.ygeno.2004.01.014. Genomics. 2004. PMID: 15203214

5

Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.

Askew DJ, Askew YS, Kato Y, Turner RF, Dewar K, Lehoczky J, Silverman GA. Askew DJ, et al. Among authors: askew ys. Genomics. 2004 Jul;84(1):176-84. doi: 10.1016/j.ygeno.2004.01.015. Genomics. 2004. PMID: 15203215

6

SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.

Askew DJ, Cataltepe S, Kumar V, Edwards C, Pace SM, Howarth RN, Pak SC, Askew YS, Brömme D, Luke CJ, Whisstock JC, Silverman GA. Askew DJ, et al. Among authors: askew ys. J Biol Chem. 2007 Aug 24;282(34):24948-60. doi: 10.1074/jbc.M703182200. Epub 2007 Jun 11. J Biol Chem. 2007. PMID: 17562709 Free article.

7

Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

Silverman GA, Whisstock JC, Askew DJ, Pak SC, Luke CJ, Cataltepe S, Irving JA, Bird PI. Silverman GA, et al. Among authors: askew dj. Cell Mol Life Sci. 2004 Feb;61(3):301-25. doi: 10.1007/s00018-003-3240-3. Cell Mol Life Sci. 2004. PMID: 14770295 Free PMC article. Review.

8

Selective conservation of the RSL-encoding, proteinase inhibitory-type, clade L serpins in Caenorhabditis species.

Luke CJ, Pak SC, Askew DJ, Askew YS, Smith JE, Silverman GA. Luke CJ, et al. Among authors: askew dj, askew ys. Front Biosci. 2006 Jan 1;11:581-94. doi: 10.2741/1820. Front Biosci. 2006. PMID: 16146754

9

Intracellular and extracellular serpins modulate lung disease.

Askew DJ, Silverman GA. Askew DJ, et al. J Perinatol. 2008 Dec;28 Suppl 3(Suppl 3):S127-35. doi: 10.1038/jp.2008.150. J Perinatol. 2008. PMID: 19057604 Free PMC article. Review.

10

An intracellular serpin regulates necrosis by inhibiting the induction and sequelae of lysosomal injury.

Luke CJ, Pak SC, Askew YS, Naviglia TL, Askew DJ, Nobar SM, Vetica AC, Long OS, Watkins SC, Stolz DB, Barstead RJ, Moulder GL, Brömme D, Silverman GA. Luke CJ, et al. Among authors: askew dj, askew ys. Cell. 2007 Sep 21;130(6):1108-19. doi: 10.1016/j.cell.2007.07.013. Cell. 2007. PMID: 17889653 Free PMC article.

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