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Page 1
Antitumor efficacy of 26-fluoroepothilone B against human prostate cancer xenografts.
Newman RA, Yang J, Raymond M, Finlay V, Cabral F, Vourloumis D, Stephens LC, Troncoso P, Wu X, Logothetis CJ, Nicolaou KC, Navone NM. Newman RA, et al. Among authors: vourloumis d. Cancer Chemother Pharmacol. 2001 Oct;48(4):319-26. doi: 10.1007/s002800100323. Cancer Chemother Pharmacol. 2001. PMID: 11710633
Total Synthesis and Biological Evaluation of Natural and Designed Tubulysins.
Nicolaou KC, Yin J, Mandal D, Erande RD, Klahn P, Jin M, Aujay M, Sandoval J, Gavrilyuk J, Vourloumis D. Nicolaou KC, et al. Among authors: vourloumis d. J Am Chem Soc. 2016 Feb 10;138(5):1698-708. doi: 10.1021/jacs.5b12557. Epub 2016 Feb 1. J Am Chem Soc. 2016. PMID: 26829208
Improved Total Synthesis of Tubulysins and Design, Synthesis, and Biological Evaluation of New Tubulysins with Highly Potent Cytotoxicities against Cancer Cells as Potential Payloads for Antibody-Drug Conjugates.
Nicolaou KC, Erande RD, Yin J, Vourloumis D, Aujay M, Sandoval J, Munneke S, Gavrilyuk J. Nicolaou KC, et al. Among authors: vourloumis d. J Am Chem Soc. 2018 Mar 14;140(10):3690-3711. doi: 10.1021/jacs.7b12692. Epub 2018 Jan 30. J Am Chem Soc. 2018. PMID: 29381062
Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues.
Nicolaou KC, Krieger J, Murhade GM, Subramanian P, Dherange BD, Vourloumis D, Munneke S, Lin B, Gu C, Sarvaiaya H, Sandoval J, Zhang Z, Aujay M, Purcell JW, Gavrilyuk J. Nicolaou KC, et al. Among authors: vourloumis d. J Am Chem Soc. 2020 Sep 9;142(36):15476-15487. doi: 10.1021/jacs.0c07094. Epub 2020 Aug 27. J Am Chem Soc. 2020. PMID: 32852944
Synthesis of epothilones A and B in solid and solution phase.
Nicolaou KC, Winssinger N, Pastor J, Ninkovic S, Sarabia F, He Y, Vourloumis D, Yang Z, Li T, Giannakakou P, Hamel E. Nicolaou KC, et al. Among authors: vourloumis d. Nature. 1997 May 15;387(6630):268-72. doi: 10.1038/387268a0. Nature. 1997. PMID: 9153390
Chemical Biology of Epothilones.
Nicolaou KC, Roschangar F, Vourloumis D. Nicolaou KC, et al. Among authors: vourloumis d. Angew Chem Int Ed Engl. 1998 Aug 17;37(15):2014-2045. doi: 10.1002/(SICI)1521-3773(19980817)37:15<2014::AID-ANIE2014>3.0.CO;2-2. Angew Chem Int Ed Engl. 1998. PMID: 29711063 Review.
48 results