Hammer RE - Search Results

1

Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene.

Yang J, Goldstein JL, Hammer RE, Moon YA, Brown MS, Horton JD. Yang J, et al. Among authors: hammer re. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13607-12. doi: 10.1073/pnas.201524598. Proc Natl Acad Sci U S A. 2001. PMID: 11717426 Free PMC article.

2

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c.

Liang G, Yang J, Horton JD, Hammer RE, Goldstein JL, Brown MS. Liang G, et al. Among authors: hammer re. J Biol Chem. 2002 Mar 15;277(11):9520-8. doi: 10.1074/jbc.M111421200. Epub 2002 Jan 8. J Biol Chem. 2002. PMID: 11782483 Free article.

3

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis.

Engelking LJ, Kuriyama H, Hammer RE, Horton JD, Brown MS, Goldstein JL, Liang G. Engelking LJ, et al. Among authors: hammer re. J Clin Invest. 2004 Apr;113(8):1168-75. doi: 10.1172/JCI20978. J Clin Invest. 2004. PMID: 15085196 Free PMC article.

4

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.

Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD. Rashid S, et al. Among authors: hammer re. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5374-9. doi: 10.1073/pnas.0501652102. Epub 2005 Apr 1. Proc Natl Acad Sci U S A. 2005. PMID: 15805190 Free PMC article.

5

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.

Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS. Engelking LJ, et al. Among authors: hammer re. J Clin Invest. 2005 Sep;115(9):2489-98. doi: 10.1172/JCI25614. Epub 2005 Aug 11. J Clin Invest. 2005. PMID: 16100574 Free PMC article.

6

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice.

Moon YA, Hammer RE, Horton JD. Moon YA, et al. Among authors: hammer re. J Lipid Res. 2009 Mar;50(3):412-423. doi: 10.1194/jlr.M800383-JLR200. Epub 2008 Oct 6. J Lipid Res. 2009. PMID: 18838740 Free PMC article.

7

Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase.

Owen JL, Zhang Y, Bae SH, Farooqi MS, Liang G, Hammer RE, Goldstein JL, Brown MS. Owen JL, et al. Among authors: hammer re. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16184-9. doi: 10.1073/pnas.1213343109. Epub 2012 Aug 27. Proc Natl Acad Sci U S A. 2012. PMID: 22927400 Free PMC article.

8

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice.

Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD. Rong S, et al. Among authors: hammer re. Elife. 2017 Feb 28;6:e25015. doi: 10.7554/eLife.25015. Elife. 2017. PMID: 28244871 Free PMC article.

9

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL. Shimano H, et al. Among authors: hammer re. J Clin Invest. 1996 Oct 1;98(7):1575-84. doi: 10.1172/JCI118951. J Clin Invest. 1996. PMID: 8833906 Free PMC article.

10

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL. Shimano H, et al. Among authors: hammer re. J Clin Invest. 1997 Mar 1;99(5):846-54. doi: 10.1172/JCI119248. J Clin Invest. 1997. PMID: 9062341 Free PMC article.

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