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ASPP proteins specifically stimulate the apoptotic function of p53.
Samuels-Lev Y, O'Connor DJ, Bergamaschi D, Trigiante G, Hsieh JK, Zhong S, Campargue I, Naumovski L, Crook T, Lu X. Samuels-Lev Y, et al. Mol Cell. 2001 Oct;8(4):781-94. doi: 10.1016/s1097-2765(01)00367-7. Mol Cell. 2001. PMID: 11684014 Free article.
iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.
Bergamaschi D, Samuels Y, O'Neil NJ, Trigiante G, Crook T, Hsieh JK, O'Connor DJ, Zhong S, Campargue I, Tomlinson ML, Kuwabara PE, Lu X. Bergamaschi D, et al. Nat Genet. 2003 Feb;33(2):162-7. doi: 10.1038/ng1070. Epub 2003 Jan 13. Nat Genet. 2003. PMID: 12524540
To die or not to die: how does p53 decide?
Slee EA, O'Connor DJ, Lu X. Slee EA, et al. Oncogene. 2004 Apr 12;23(16):2809-18. doi: 10.1038/sj.onc.1207516. Oncogene. 2004. PMID: 15077144 Review.
100 results